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Case Reports
. 2022 Feb 15:17:100293.
doi: 10.1016/j.lrr.2022.100293. eCollection 2022.

A new approach in acute myeloid leukemia (AML): Samatya-predicting score

Istemi Serin  1 , Bagnu Orhan  2 , Derya Sonmez  2 , Tahir Alper Cinli  1 , Hasan Goze  1 , Huriye Serin  2 , Begum Gulesir  3 , Osman Yokus  1
Affiliations
Case Reports

A new approach in acute myeloid leukemia (AML): Samatya-predicting score

Istemi Serin et al. Leuk Res Rep. .

Abstract

We aimed to examine the efficiency for prediction of prognosis and response in non-APL AML cases of the "Samatya-predicting score". A total of 213 patients diagnosed between January 2010-December 2020 were examined. Of the 158 patients included in the study, the median value of risk score was determined as 2,5. The sensitivity for mortality was 88% and the specificity was 42%. In terms of being non-responder to induction therapy, the sensitivity was 90,1%, the specificity was 25,3%. OS was shorter in those with high risk scores. This study makes an important contribution to the literature in terms of creating a different perspective to predict prognosis in AML.

Keywords: Acute myeloid leukemia; Flow cytometry; Prognosis; Response.

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Conflict of interest statement

None to declare.

Figures

Fig. 1
Fig. 1
Patients’ flow-chart.
Fig. 2
Fig. 2
(A) ROC curve for mortality, (B) ROC curve for response status.
Fig. 3
Fig. 3
Kaplan-Meier Curves: (A) Survival by risk score for mortality, (B) Survival by risk score for response.
See this image and copyright information in PMC

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