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Case Reports
. 2022 Feb 25:27:e01460.
doi: 10.1016/j.idcr.2022.e01460. eCollection 2022.

Use of tafenoquine to treat a patient with relapsing babesiosis with clinical and molecular evidence of resistance to azithromycin and atovaquone

Luis A Marcos  1 , Annie Leung  2 , Laura Kirkman  2 , Gary P Wormser  3
Affiliations
Case Reports

Use of tafenoquine to treat a patient with relapsing babesiosis with clinical and molecular evidence of resistance to azithromycin and atovaquone

Luis A Marcos et al. IDCases. .

Abstract

Tafenoquine is a highly effective treatment for Babesia microti infections in animal models. An immunocompromised patient infected by a strain of B. microti that was at least partially resistant to both azithromycin and atovaquone was treated with tafenoquine. Systematic clinical studies using tafenoquine for treating other patients with babesiosis should be considered.

Keywords: Antibiotic resistance; Babesia microti; Babesiosis; Rituximab; Tafenoquine.

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