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Comment
. 2022 Feb 15;3(2):100531.
doi: 10.1016/j.xcrm.2022.100531.

Teach 'em young: Influenza vaccines induce broadly neutralizing antibodies in children

Haley L Dugan  1 , Patrick C Wilson  2
Affiliations
Comment

Teach 'em young: Influenza vaccines induce broadly neutralizing antibodies in children

Haley L Dugan et al. Cell Rep Med. .

Abstract

Antibodies against the influenza virus hemagglutinin stalk afford broad protection against antigenically drifted viruses. In this issue of Cell Reports Medicine, Yegorov et al.1 identify that current vaccine formulations induce neutralizing stalk antibodies in children-a highly vulnerable population.

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Conflict of interest statement

H.L.D. is an employee of Adimab, LLC, and may hold shares in Adimab, LLC. P.C.W. is a consultant for Adagio Therapeutics, Inc.

Comment on

References

    1. Yegorov S., Celeste D.B., Braz Gomes K., Ang J.C., Vandenhof C., Wang J., Rybkina K., Tsui V., Stacey H.D., Loeb M., et al. Inactivated and live-attenuated seasonal influenza vaccines boost broadly neutralizing antibodies in children. Cell Rep Med. 2022;3:100509-1–100509-11. - PMC - PubMed
    1. Chambers B.S., Parkhouse K., Ross T.M., Alby K., Hensley S.E. Identification of Hemagglutinin Residues Responsible for H3N2 Antigenic Drift during the 2014-2015 Influenza Season. Cell Rep. 2015;12:1–6. - PMC - PubMed
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