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. 2022 Aug;43(6):1379-1382.
doi: 10.1007/s00246-022-02863-7. Epub 2022 Mar 5.

Decreased Risk of Strokes in Children with Ventricular Assist Devices Within ACTION

David M Peng  1 , Muhammad F Shezad  2 , Angela Lorts  2 , Robert J Gajarski  3 , Christina VanderPluym  4 , Jenna M Murray  5 , Beth Hawkins  4 , Chet R Villa  2 , Farhan Zafar  2 , David N Rosenthal  5 ; ACTION
Affiliations

Decreased Risk of Strokes in Children with Ventricular Assist Devices Within ACTION

David M Peng et al. Pediatr Cardiol. 2022 Aug.

Abstract

We sought to characterize strokes in children with ventricular assist devices. Of 407 patients in the ACTION registry (4/1/18-5/3/2021), 45 (11%) experienced 52 strokes (45 ischemic and 7 hemorrhagic). Median time to stroke was 23.5 days and 19/52 (37%) occurred ≤ 10 days. Stroke rate was 0.09 and 0.63 strokes per patient-year for implantable continuous and paracorporeal devices, respectively. Patients with stroke were younger, more likely to have congenital heart disease and have been on extracorporeal membrane oxygenation at time of VAD. Based on these data, ACTION is now focused on decreasing strokes in these higher-risk patients with particular attention to the peri-implant period.

Keywords: Pediatrics; Quality improvement; Stroke; Ventricular assist devices.

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References

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