HW reports personal fees from Falk Foundation, Gore, Intercept, Pfizer, Merz, and Norgine; and grants from Merz and from Norgine, unrelated to this Correspondence. W-KC reports personal fees from Abbvie, Novo Nordisk, Boehringer Ingelheim, Viatris, and Hisky Medical, unrelated to this Correspondence. TK reports honorarium for lectures from Janssen Pharmaceutical KK, Mitsubishi Tanabe Pharma Corporation, Otsuka Pharmaceutical, and EA Pharma, unrelated to this Correspondence. LC reports personal fees from Alexion, AbbVie, Echosens, Gilead, Intercept, Merck, Novo Nordisk, and Pfizer; and grants from Gilead, unrelated to this Correspondence. MHN reports grants from Glycotest, Gilead, Pfizer, Enanta, BK Kee Foundation, National Cancer Institute, and Vir Biotech; and personal fees from Spring Bank, Novartis, Janssen Eisai, Bayer, Intercept, Exact Science, Laboratory of Advanced Medicine, Helio, and Eli Lilly. MHN also reports acting as a consultant or on an advisory board for Gilead, unrelated to this Correspondence. LV reports grants from Gilead and personal fees from Viatris, unrelated to this Correspondence. RGG has received grants or research support in past 2 years from Gilead. RGG has also performed as a consultant or advisor in the past 2 years to Abbott, AbbVie, Altimunne, Antios, Arrowhead, Dynavax, Eiger, Eisai, Enyo, Genentech, Genlantis, Gerson Lehrman Group, Gilead Sciences, Helios, HepaTX, HepQuant, Intercept, Janssen, Merck, Pfizer, Topography Health, and Venatorx. RGG is on scientific or clinical advisory boards for AbbVie, Antios, Dynavax, Enyo, Genentech, Genlantis, Gilead, Helios, HepaTX, HepQuant, Intercept, Janssen, Merck, Pfizer, and Prodigy. RGG has performed as a consultant, advisor, or both to Topography Health. RGG is chair of the clinical advisory board for Prodigy. RGG is an advisory consultant for Fibronostics, Fujifilm–Wako, Perspectum, Quest, and Sonic Incytes. RGG is on data safety monitoring boards for Altimmune, Arrowhead, CymaBay Therapeutics, and Durect. RGG currently has consulting confidentiality agreements with AbbVie, Abbott, Access Biologicals, ADMA Biologics, AEC Partners, Aligos Therapeutics, Arena Pharmaceuticals, ArrowHead, Arterys, Alexion, Altimmune, Antios Therapeutics, AprosTx, Bayer, Cirina, Consumer Health Products Association, CymaBay Therapeutics, DiaSorin, Dova Pharmaceuticals, DRG Abacus, Durect, Dynavax, Echosens, Eiger, Enyp, Exelixis, Fibronostics, Forty-Seven, Fujifilm Wako Diagnostics, Gilead Sciences, HepQuant, HepaTx, IDLogiq, Intellia, Intercept, Inotek, Iqvia, Janssen–Johnson & Johnson, KannaLife, Laboratory for Advanced Medicine, Labyrinth, Life Line Screening, Eli Lilly, MedImmne, Merck, New Enterprise Associates, Ogilvy CommonHealth, Organovo, Patient Connect, Prodigy Biotech, Prometheus Laboratories, Refuah Solutions, Regulus Therapeutics, Salix, Shionogi, Spring Bank, and Trimaran. RGG has speaker's contracts to do promotional talks for AbbVie, Bristol Myers Squibb, Eisai, Gilead Sciences, and Intercept. RGG is a minor stock shareholder (only for projects in the liver field but not fatty liver disease-related areas) for RiboSciences and CoCrystal. RGG holds stock options in Eiger, Genlantis, HepQuant, and AngioCrine, unrelated to this Correspondence. All other authors declare no competing interests.