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Review
. 2022 Jun 1:162:111763.
doi: 10.1016/j.exger.2022.111763. Epub 2022 Mar 3.

Role of fruits in aging and age-related disorders

Muhammad Usman Arif  1 , Muhammad Kashif Iqbal Khan  1 , Sana Riaz  1 , Akmal Nazir  2 , Abid Aslam Maan  3 , Usman Amin  1 , Farhan Saeed  4 , Muhammad Afzaal  4
Affiliations
Review

Role of fruits in aging and age-related disorders

Muhammad Usman Arif et al. Exp Gerontol. .

Abstract

Aging is a collection of changes that contribute to decline in maximum function and ultimately death of an organism. This process is controlled and initiated by several mechanisms including telomere shortening, oxidative stress, AMP-activated protein kinase and sirt-1. Several therapies have been reported to relieve the process of aging. Among these, diet therapy seems to be the most appropriate approach. Fruits are an important part of regular diet. They contain several compounds which have potential to handle the problem of aging and its related disorders. The present paper provides a comprehensive review on different factors present in various fruits related to the process of aging together with their antiaging mechanisms.

Keywords: AMPK; Aging; Oxidative stress; Reactive oxygen spices; Sirt 1; Telomere.

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