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Review
. 2022 May 1;31(3):258-264.
doi: 10.1097/MNH.0000000000000791. Epub 2022 Mar 4.

Updates in hypertension: new trials, targets and ways of measuring blood pressure

Liann Abu Salman  1 , Jordana B Cohen  1   2
Affiliations
Review

Updates in hypertension: new trials, targets and ways of measuring blood pressure

Liann Abu Salman et al. Curr Opin Nephrol Hypertens. .

Abstract

Purpose of review: Several recent trials and observational studies have identified critical areas that can help to improve the management and measurement of blood pressure in patients with hypertension.

Recent findings: High-quality trial evidence supports intensive SBP lowering to 110-130 mmHg in older patients, potassium- based salt substitution in patients without chronic kidney disease, and chlorthalidone for the management of hypertension in patients with chronic kidney disease. In addition, population-based studies indicate enormous underdiagnosis of primary aldosteronism as well as greater sustained intensification of antihypertensive therapy in older patients by maximizing medication dosage rather than adding new agents. The prevalence of hypertension is stable worldwide, though is generally improving in high-income countries and worsening in low-income countries. Furthermore, although cuffless blood pressure devices have the potential to improve access to blood pressure measurement, they have not yet demonstrated sufficient accuracy for clinical use.

Summary: Growing evidence supports intensive blood pressure lowering, sodium reduction, targeted antihypertensive treatment and appropriate screening for secondary hypertension to optimize blood pressure control and reduce the risk of target organ damage from hypertension. Future studies are needed to identify ways to improve our ability to implement these findings in routine clinical practice.

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Conflict of interest statement

Conflicts of interest

Both authors report no relevant conflicts of interest.

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References

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