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. 2022 Mar 2:12:e2021363.
doi: 10.4322/acr.2021.363. eCollection 2022.

Neuro-toxoplasmosis and fatal necrotizing cerebellitis

Gabriele Gaggero  1 , Michela Campora  2 , Beatrice Dose  3 , Davide Taietti  4 , Antonio Vena  5 , Emanuele Delfino  5
Affiliations

Neuro-toxoplasmosis and fatal necrotizing cerebellitis

Gabriele Gaggero et al. Autops Case Rep. .
No abstract available

Keywords: Central Nervous System Infections; Central Nervous System Protozoal Infections; Cerebellar Diseases; Toxoplasmosis, Cerebral.

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Conflict of interest statement

Conflict of interest: None.

Figures

Figure 1
Figure 1. A – Cerebellar cutting (after formalin fixation): sagittal cut shows reddish friable area involving cerebellar folia (arrows); B – Axial cut shows reddish softened areas involving both cerebellar hemispheres and the cerebellar vermis; C – Microscopic view: at low magnification (Periodic Acid Schiff, magnification: 5x), a more intensely stained area is observed at the level of the cerebellar folia (arrow); D – Microscopic view: at higher magnification (H&E, magnification: 60x), this cerebellar area shows - at the transition between the granular layer and the molecular layer - the presence of necrosis and dark round corpuscles, consistent in size and morphology with Toxoplasma, both in the pseudocystic bradyzoite form (arrows) and in the dispersed/single tachyzoite form (arrowheads).
See this image and copyright information in PMC

References

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