Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Apr;29(2):125-133.
doi: 10.1177/15910199221081243. Epub 2022 Mar 7.

Stentrievers : An engineering review

Syed Uzair Ahmed  1 , Xiongbiao Chen  2 , Lissa Peeling  1 , Michael E Kelly  1   2
Affiliations
Review

Stentrievers : An engineering review

Syed Uzair Ahmed et al. Interv Neuroradiol. 2023 Apr.

Abstract

The advent of endovascular therapy for acute large vessel occlusion has revolutionized stroke treatment. Timely access to endovascular therapy, and the ability to restore intracranial flow in a safe, efficient, and efficacious manner has been critical to the success of the thrombectomy procedure. The stentriever has been a mainstay of endovascular stroke therapy, and current guidelines recommend the usage of stentrievers in the treatment of large vessel occlusion stroke. Despite the success of existing stentrievers, there continues to be significant development in the field, with newer stentrievers attempting to improve on each of the three key aspects of the thrombectomy procedure. Here, we elucidate the technical requirements that a stentriever must fulfill. We then review the basic variables of stent design, including the raw material and its form, fabrication method, geometric configuration, and further additions. Lastly, a selection of stentrievers from successive generations are reviewed using these engineering parameters, and clinical data is presented. Further avenues of stentriever development and testing are also presented.

Keywords: Stentriever; acute ischemic stroke; device design; large vessel occlusion; mechanical thrombectomy.

PubMed Disclaimer

Conflict of interest statement

The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Michael E. Kelly, consultant for Imperative Care and Cerenovus. All other authors confirm no conflicts of interest.

Figures

Figure 1.
Figure 1.
A. Solitaire X device; B and C. Device overlap profile with varying vessel diameter for Solitaire X 6mm (B) and Solitaire X 4mm (C)..
Figure 2.
Figure 2.
Trevo stentriever.,.
Figure 3.
Figure 3.
The Embotrap III revascularization device in 5 × 22mm, 5 × 37mm, and 6.5 × 45mm sizes. .
Figure 4.
Figure 4.
A And B. The Penumbra 3D Revascularization Device..
See this image and copyright information in PMC

References

    1. Berkhemer OA, Fransen PS, Beumer D, et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015; 372: 11–20. - PubMed
    1. Campbell BC, Mitchell PJ, Kleinig TJ, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015; 372: 1009–1018. - PubMed
    1. Goyal M, Demchuk AM, Menon BK, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 2015; 372: 1019–1030. - PubMed
    1. Jovin TG, Chamorro A, Cobo E, et al. Thrombectomy within 8 h after symptom onset in ischemic stroke. N Engl J Med 2015; 372: 2296–2306. - PubMed
    1. Saver JL, Goyal M, Bonafe A, et al. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 2015; 372: 2285–2295. - PubMed