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Editorial
. 2022 Mar 1;12(3):602-603.
doi: 10.1158/2159-8290.CD-21-1642.

Are You a TMBeliever? Mutations and Atezolizumab Response in Solid Tumors

Steven B Maron  1 , Samuel J Klempner  2
Affiliations
Editorial

Are You a TMBeliever? Mutations and Atezolizumab Response in Solid Tumors

Steven B Maron et al. Cancer Discov. .

Abstract

Optimizing the utility of tumor mutational burden in solid tumors remains an unmet need and a clinical knowledge gap. Using a centrally determined cutoff of ≥16 mut/Mb, Friedman and colleagues demonstrate an ability to enrich for atezolizumab response in a pretreated pan-cancer multibasket study. See related article by Friedman et al., p. 654 (4).

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