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Case Reports
. 2022 May;56(4):448-453.
doi: 10.1177/15385744221077824. Epub 2022 Mar 8.

Angiosarcoma of a Femoropopliteal Bypass Thrombosed Vein Graft

Carlos Veterano  1 , Sérgio Teixeira  1   2 , Ivone Silva  1   2   3 , Andreia Coelho  1 , Rui Almeida  1   2   3 , Pedro Sá Pinto  1   2
Affiliations
Case Reports

Angiosarcoma of a Femoropopliteal Bypass Thrombosed Vein Graft

Carlos Veterano et al. Vasc Endovascular Surg. 2022 May.

Abstract

Background: Angiosarcoma is a rare subtype of malignant vascular tumours which has been only anecdotally described in patients submitted to lower limb revascularization.

Case presentation: This paper reports a patient previously submitted to a femoropopliteal bypass using autologous great saphenous vein (GSV). Nine years after the initial surgery, a primary angiosarcoma of the thrombosed vein graft was diagnosed, requiring en bloc surgical resection. Rampant metastatic spread was documented despite primary tumour surgical resection with a dismal outcome within months.

Conclusions: Malignant transformation of autologous vein for lower limb revascularization is extremely rare and anecdotally described in the literature. It is a poorly studied complication with an aggressive behaviour. This report further reinforces the need for early recognition of this pathology.

Keywords: chronic limb-threatening ischaemia; revascularization; sarcoma; vein.

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