Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023;26(1):3-13.
doi: 10.2174/1386207325666220308153732.

Thuja occidentalis: An Unexplored Phytomedicine with Therapeutic Applications

Affiliations
Review

Thuja occidentalis: An Unexplored Phytomedicine with Therapeutic Applications

Ankit Srivastava et al. Comb Chem High Throughput Screen. 2023.

Abstract

Background: The recent outbreak of SARS-CoV-2 has received global attention. Due to a lack of recommended treatment regimens, the world faced various limitations resulting in improper management of the disease. Phytomedicines have played a prominent role in the prevention of various epidemics and pandemics in the past.

Objective: Here, we attempt to focus on safe and feasible use of Thuja occidentalis to manage and alleviate the panic of viral respiratory infections, including COVID-19, by strengthening an individual's immunity. The relevant information was collected from the web-based databases PubMed, Google Scholar, and MEDLINE, as well as other internet sources to review the applicability of T. occidentalis as a phytomedicine in managing respiratory infections and strengthening immunity.

Conclusion: As important phytomedicine, and antipsychotic, T. occidentalis possesses a plethora of immunological properties that can be used effectively in the management of viral respiratory infections and has the potential to prevent further progression of the disease. Importantly, this could be only a part of the approach for treatment during the current outbreak that should be considered along with other measures.

Keywords: COVID-19; Phytomedicine; Thuja occidentalis; antiviral; immunity; immunomodulatory; upper respiratory infection.

PubMed Disclaimer

Similar articles

Cited by

  • Kaempferol: A Review of Current Evidence of Its Antiviral Potential.
    Periferakis A, Periferakis AT, Troumpata L, Periferakis K, Scheau AE, Savulescu-Fiedler I, Caruntu A, Badarau IA, Caruntu C, Scheau C. Periferakis A, et al. Int J Mol Sci. 2023 Nov 14;24(22):16299. doi: 10.3390/ijms242216299. Int J Mol Sci. 2023. PMID: 38003488 Free PMC article. Review.

References

    1. Hui D.S.; Azhar I.; E.; Madani, T.A.; Ntoumi, F.; Kock, R.; Dar, O.; Ippolito, G.; Mchugh, T.D.; Memish, Z.A.; Drosten, C.; Zumla, A.; Petersen, E. The continuing 2019-nCoV epi-demic threat of novel coronaviruses to global health - The lat-est 2019 novel coronavirus outbreak in Wuhan, China. Int J Infect Dis 2020,91,264-266 - DOI - PubMed
    1. WHO coronavirus (COVID-19) dashboard | WHO coronavirus (COVID-19) Dashboard with vaccination data. Available from: (Accessed: August 30, 2021).
    1. Clinical Management Protocol for COVID19. Available from: (Accessed: June 27, 2020).
    1. Shi Y.; Wang Y.; Shao C.; Huang J.; Gan J.; Huang X.; Bucci E.; Piacentini M.; Ippolito G.; Melino G.; COVID-19 infection: The perspectives on immune responses. Cell Death Differ 2020,27(5),1451-1454 - DOI - PubMed
    1. Jit B.P.; Qazi S.; Arya R.; Srivastava A.; Gupta N.; Sharma A.; An immune epigenetic insight to COVID-19 infection. Epigenomics 2021,13(6),465-480 - DOI - PubMed

Substances