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Review
. 2022 May-Jun;16(3):253-260.
doi: 10.1016/j.jacl.2022.02.005. Epub 2022 Feb 20.

Hyperlipidemia and risk for preclampsia

Indu G Poornima  1 , Mahathi Indaram  2 , Joyce D Ross  3 , Anandita Agarwala  4 , Robert A Wild  5
Affiliations
Review

Hyperlipidemia and risk for preclampsia

Indu G Poornima et al. J Clin Lipidol. 2022 May-Jun.

Abstract

Hypertensive disorders of pregnancy are among the leading causes of maternal morbidity and mortality in the US. Preeclampsia (PreE) which includes hypertension and proteinuria during pregnancy, is thought to result from placental ischemia. Risk factors for PreE parallel those for cardiovascular disease, and recent studies point to hyperlipidemia specifically, hypertriglyceridemia, as a risk factor for PreE. Current practice does not routinely include lipid testing pre-conception or during pregnancy. Professional, societal recommendations should advocate for hyperlipidemia screening, followed by appropriate management, pre-conception and during pregnancy.

Keywords: Hypertriglyceridemia; Lipid testing; Maternal morbidity; Preeclampsia; Pregnancy.

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Conflict of interest statement

Conflict of interest: All Authors have no conflicts to disclose that are relevant to this publication.

Figures

Figure 1
Figure 1
Changes in lipid fractions through normal pregnancy and postpartum.
See this image and copyright information in PMC

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