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. 2022 Jan-Feb;27(1):60-64.
doi: 10.4103/jiaps.JIAPS_319_20. Epub 2022 Jan 11.

Efficacy of Core Needle Biopsy in the Diagnosis of Pediatric Extracranial Solid Malignancies: A 10-Year Study

Arun Kumar Loganathan  1 , Tarun John Jacob  1 , Leni Grane Matthew  2 , Vinu Moses  3 , Shyam Kumar Nidugala Keshava  3 , Anne Jennifer Priscilla  4 , Jujju Jacob Kurian  1
Affiliations

Efficacy of Core Needle Biopsy in the Diagnosis of Pediatric Extracranial Solid Malignancies: A 10-Year Study

Arun Kumar Loganathan et al. J Indian Assoc Pediatr Surg. 2022 Jan-Feb.

Abstract

Introduction: Core needle biopsies of solid masses in children are a minimally invasive technique. It guides to a definitive diagnosis and facilitates management.

Aims and objectives: To determine the accuracy, sensitivity, and specificity of core needle biopsies in diagnosing pediatric solid masses.

Materials and methods: A retrospective analysis of 430 children, who underwent core needle biopsy for solid masses between January 2007 and December 2016 at CMC Vellore, was done.

Results: Retroperitoneal and intra-abdominal masses constituted 66% of cases. Real-time image guidance was used in 44% of cases. An accurate diagnosis was obtained in 93.6% of cases, while results did not correlate with the final diagnosis in 3.4%. Three percent had inadequate or necrotic tissue. None of the children had postprocedure complications.

Conclusion: Core needle biopsies serve as good diagnostic modality, with minimal risks, in making a conclusive diagnosis and deciding on the line of management.

Keywords: Core needle biopsy; image-guided biopsy; solid malignancies.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Flowchart showing the number of core needle biopsies done and the results (WG: Without real time image guidance, USG: Ultrasound guided, CT: Computed Tomography guided)
See this image and copyright information in PMC

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