Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Dec;59(4):282-288.
doi: 10.4274/tao.2021.2021-8-13. Epub 2022 Feb 22.

En Bloc Resection of Supraglottic Carcinomas with Transoral Laser Microsurgery

Kerem Öztürk  1 , Arin Öztürk  1 , Göksel Turhal  1
Affiliations

En Bloc Resection of Supraglottic Carcinomas with Transoral Laser Microsurgery

Kerem Öztürk et al. Turk Arch Otorhinolaryngol. 2021 Dec.

Abstract

Objective: Complete en bloc supraglottic tumor excision with transoral laser microsurgery (TLM) can be achieved with good postoperative outcomes. We report surgical feasibility and the postsurgical outcomes of en bloc resection of supraglottic laryngeal squamous cell carcinomas (LSCC) with TLM.

Methods: Seventeen patients who underwent TLM for supraglottic laryngeal cancer were included in the study. Demographic and pathological data, clinic and follow-up outcomes of the patients were reviewed and analyzed.

Results: Type 1 TLM was performed in three patients, type 2a in one patient, type 3b in 12 patients, and type 4b in one patient. Negative surgical margins were achieved in all of the cases. Re-excision or any adjuvant treatment for positive resection margins was not required in any of the cases. Eight patients received adjuvant radiotherapy due to lymph node metastasis. Mean follow-up time was 33.8±15.7 months (range: 10-65 months). None of the patients had recurrence or distant metastasis.

Conclusion: The transoral approach with the use of CO2 laser and microscopy offers complete tumor excision for treating supraglottic LSCC. The three-dimensional structure of the supraglottis can be achieved with adequate exposure. En bloc resection is possible with safe margins.

Keywords: Larynx carcinoma; partial laryngectomy; squamous cell carcinoma; supraglottic carcinoma; transoral laser microsurgery.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

Figure 1
Figure 1
Surgical specimen of patient number 3. The tumor was located on the left side of the infrahyoid epiglottis. Type 3b transoral supraglottic laryngectomy (SGL) was performed
Figure 2
Figure 2
Surgical specimen of patient number 16. The tumor was on the laryngeal surface of the infrahyoid epiglottis, extending to the petiole
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Zeitels SM, Vaughan CW, Domanowski GF. Endoscopic management of early supraglottic cancer. Ann Otol Rhinol Laryngol. 1990;99:951–6. - PubMed
    1. Iro H, Waldfahrer F, Altendorf-Hofmann A, Weidenbecher M, Sauer R, Steiner W. Transoral laser surgery of supraglottic cancer: follow-up of 141 Patients. Arch Otolaryngol Head Neck Surg. 1998;124:1245–50. - PubMed
    1. Ambrosch P, Gonzalez-Donate M, Fazel A, Schmalz C, Hedderich J. Transoral laser microsurgery for supraglottic cancer. Front Oncol. 2018;8:158. - PMC - PubMed
    1. Peretti G, Piazza C, Cattaneo A, De Benedetto L, Martin E, Nicolai P. Comparison of functional outcomes after endoscopic versus open-neck supraglottic laryngectomies. Ann Otol Rhinol Laryngol. 2006;115:827–32. - PubMed
    1. Roh JL, Kim DH, Park CI. Voice, swallowing and quality of life in patients after transoral laser surgery for supraglottic carcinoma. J Surg Onc. 2008;98:184–9. - PubMed