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. 2022 Jun;11(3):1047-1066.
doi: 10.1007/s40123-022-00486-y. Epub 2022 Mar 9.

Myopic LASIK Outcomes: Comparison of Three Different Femtosecond Lasers and a Mechanical Microkeratome Using the Same Excimer Laser

Juan Gros-Otero  1 , Isabel Rodríguez-Pérez  2 , Miguel A Teus  3   4 , Andreas Katsanos  5 , Dimitrios G Mikropoulos  6 , Montserrat García-González  1   3
Affiliations

Myopic LASIK Outcomes: Comparison of Three Different Femtosecond Lasers and a Mechanical Microkeratome Using the Same Excimer Laser

Juan Gros-Otero et al. Ophthalmol Ther. 2022 Jun.

Abstract

Introduction: To compare the influence of one microkeratome and three femtosecond lasers on myopic laser in situ keratomileusis (LASIK) outcomes.

Methods: Retrospective, observational cohort study. We compared 134 eyes treated with the IntraLase 60 kHz, 112 eyes treated with the Femto LDV Z6, 206 eyes treated with the FS200, and 98 eyes treated with the Hansatome zero compression microkeratome. All eyes were operated on using the same surgical protocol with the same excimer laser (Wavelight Allegretto) and were allocated to refraction-matched groups.

Results: One day and one week postoperatively, uncorrected distance visual acuity was significantly lower in the FS200 group compared to others (P = 0.0001). This difference disappeared at the 1- and 3-month postoperative visits. Significant differences were found among groups in terms of safety index (P = 0.0001), residual sphere (P = 0.0001), and residual cylinder (P = 0.02) at the 3-month postoperative visit. No significant differences were found in corrected distance visual acuity or efficacy index.

Conclusion: According to our results, a slight delay in visual restoration after FS200 LASIK surgery might be expected. This delay was statistically significant at 1 day and 1 week postoperatively, but there were no differences from the 1-month visit onwards. Additionally, significant differences were found among devices in terms of safety index and the refractive results, which were found not to be clinically relevant.

Keywords: Femtosecond LASIK; LASIK; Mechanical LASIK; Myopia.

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Figures

Fig. 1
Fig. 1
Cumulative histogram of uncorrected distance visual acuity 3 months after myopic LASIK for the IntraLase (a), Femto LDV (b), FS200 (c), and Hansatome (d) groups. LASIK laser in situ keratomileusis, UDVA uncorrected distance visual acuity, CDVA corrected distance visual acuity
Fig. 2
Fig. 2
Changes in lines of corrected distance visual acuity 3 months after myopic LASIK for the IntraLase (a), Femto LDV (b), FS200 (c), and Hansatome (d) groups. LASIK laser in situ keratomileusis, CDVA corrected distance visual acuity
Fig. 3
Fig. 3
Three-month predictability (spherical equivalent ± 0.5 D and spherical equivalent ± 1 D) after myopic LASIK for the IntraLase (a), Femto LDV (b), FS200 (c), and Hansatome (d) groups. LASIK laser in situ keratomileusis, D diopters
Fig. 4
Fig. 4
Attempted versus achieved spherical equivalent refraction scatterplots 3 months after LASIK for myopia correction for the IntraLase (a), Femto LDV (b), FS200 (c), and Hansatome (d) groups. The linear regression equation and coefficient of determination (R2) are displayed. Intra-group linear regression analysis test. LASIK laser in situ keratomileusis, D diopters
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References

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