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. 2022 Feb 15;135(13):1539-1544.
doi: 10.1097/CM9.0000000000001942. Online ahead of print.

Acute carbon monoxide poisoning in Shandong, China: an observational study

Lina Zhang  1   2 , Di Wu  2 , Mingyue Xu  2   3 , Yonghui Bian  3   4 , Youcun Wang  3   4 , Guangkai Gao  2   3 , Qing Sun  1   2
Affiliations

Acute carbon monoxide poisoning in Shandong, China: an observational study

Lina Zhang et al. Chin Med J (Engl). .

Abstract

Background: Carbon monoxide (CO) poisoning remains a major cause of accidental injuries and multiple studies have indicated that CO is also associated with significantly severe or long-term toxicity to the central nervous system. Given that CO poisoning causes serious morbidity and mortality, a better understanding of epidemiological features and clinical characteristics of acute CO poisoning in China is crucial.

Methods: We collected the clinical data of acute CO poisoning in patients between November 2019 and April 2020 across Shandong province, China and analyzed its characteristics focusing on the weekly amount and the severity of the confirmed cases.

Results: A total number of 21,088 acute CO poisoning cases were diagnosed. The overall incidence of acute CO poisoning was approximately 0.021%. On severity rankings, 63% of confirmed cases (n = 13,378) were mild, 27% (n = 5635) were moderate, and 10% (n = 2075) were severe. Interestingly, the coastal cities had more confirmed cases than the inland/suburban areas in Shandong. Meanwhile, the number of confirmed cases was negatively correlated with the local mean daily temperature (P = 0.0167).

Conclusions: Mild acute CO poisoning cases accounted for the majority of all confirmed cases during the winter of 2019. In Shandong province, which is located in east China, residents of the coastal cities are more susceptible to CO poisoning than residents of inland cities.

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Conflict of interest statement

None.

Figures

Figure 1
Figure 1
Provincial general characteristics of confirmed cases of acute CO poisoning. (A) The weekly number of total confirmed cases of acute CO poisoning. (B) Differences in distributions and characteristics of each type of acute CO poisoning. CO: Carbon monoxide.
Figure 2
Figure 2
Regional differences in characteristics of acute CO poisoning in 16 municipal cities. CO: Carbon monoxide.
Figure 3
Figure 3
Correlation between environmental temperature and number of confirmed cases of acute CO poisoning (Spearman r = -0.9429, P value = 0.0167). Each value of temperature on the X-axis represents the mean daily temperature of each month. CO: Carbon monoxide.
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