Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Mar 8;55(3):387-389.
doi: 10.1016/j.immuni.2022.02.009.

A high-resolution view of intra-tumoral B cell immunity

Xihao Hu  1 , X Shirley Liu  2
Affiliations
Free article
Comment

A high-resolution view of intra-tumoral B cell immunity

Xihao Hu et al. Immunity. .
Free article

Abstract

In this issue of Immunity, Meylan et al. (2022) uses spatial transcriptomics to examine B cell immunity within intratumoral tertiary lymphoid structures (TLSs). They find that B cells expand and mature into plasma cells (PCs) within the TLS, migrate along fibroblastic tracks to tumor beds, and produce IgG antibodies that target cancer cells.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests X.S.L. is a board member and shareholder of GV20 Oncotherapy and the CEO of its subsidiary, GV20 Therapeutics. X.H. is a shareholder of GV20 Oncotherapy and the Chief Information Officer of its subsidiary, GV20 Therapeutics.

Comment on