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. 2022 Mar 17;185(6):939-940.
doi: 10.1016/j.cell.2022.02.020. Epub 2022 Mar 8.

Mapping the long road to cancer

David M Cheek  1 , Kamila Naxerova  2
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Free article
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Mapping the long road to cancer

David M Cheek et al. Cell. .
Free article

Abstract

Every cell in our body accumulates mutations throughout life, and sometimes an unfortunate combination of mutations drives the initiation of cancer. A new study infers extraordinarily detailed timelines of pre-cancerous evolution by sequencing single-cell genomes in patients with blood malignancies-finding that key mutations can arrive decades before diagnosis.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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