Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Mar 9;23(1):99.
doi: 10.1186/s12882-022-02723-9.

Patient-reported gastrointestinal symptoms in patients with peritoneal dialysis: the prevalence, influence factors and association with quality of life

Chunyan Yi  1 , Xin Wang  1 , Hongjian Ye  1 , Jianxiong Lin  1 , Xiao Yang  2
Affiliations

Patient-reported gastrointestinal symptoms in patients with peritoneal dialysis: the prevalence, influence factors and association with quality of life

Chunyan Yi et al. BMC Nephrol. .

Abstract

Background: The aims of this study were to investigate the prevalence and the influence factors of gastrointestinal symptoms, and its association with the quality of life (QOL) in peritoneal dialysis (PD) patients.

Methods: Continuous ambulatory PD patients (CAPD) who followed up in our PD center between March 2016 and December 2017 were enrolled in this cross-sectional study. Gastrointestinal symptom rating scale (GSRS) was used to evaluate gastrointestinal symptoms. The related clinical data were also collected. Multiple linear regression analysis was test for the influence factors associated with score of GSRS and QOL.

Results: This study included 471 CAPD patients. The mean age was 48.5±13.9 years, 53.9% were male and 15.1% with diabetic nephropathy. The median duration of PD was 37.3 (17.5~66.5) months. The median score of GSRS was 1.2(1.1~1.3) scores. Totally 82.2% (n=387) CAPD patients had at least one gastrointestinal symptom. Higher glycosylated hemoglobin, higher score of depression, lower diastolic blood pressure, urine output, score of instrumental activities of daily living scale and more amount of pills per day were independently associated with higher score of GSRS (all P<0.05). Score of dyspepsia and eating dysfunction were independently associated with worse score of QOL and physical health (all P<0.05).

Conclusions: Gastrointestinal symptoms were common but not serious in CAPD patients. Glycemic control, depression, blood pressure, urine output, activity of daily life and amount of pills were all associated with gastrointestinal symptoms. Moreover, gastrointestinal symptoms were correlated with QOL of PD patients.

Keywords: Gastrointestinal symptoms; Peritoneal dialysis; Quality of life.

PubMed Disclaimer

Conflict of interest statement

All authors of this study declared that there was no conflict of interest in the publication of this article.

Figures

Fig. 1
Fig. 1
Flow chart
Fig. 2
Fig. 2
Prevalence and severity of gastrointestinal symptoms reported by peritoneal dialysis patients
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Kosmadakis G, Albaret J, Da Costa CE, Somda F, Aguilera D. Constipation in Peritoneal Dialysis Patients. Peritoneal Dialysis Int. 2019;39(5):399–404. doi: 10.3747/pdi.2018.00169. - DOI - PubMed
    1. Salamon K, Woods J, Paul E, Huggins C. Peritoneal dialysis patients have higher prevalence of gastrointestinal symptoms than hemodialysis patients. J Renal Nutr. 2013;23(2):114–118. doi: 10.1053/j.jrn.2012.02.007. - DOI - PubMed
    1. Kosmadakis G, Albaret J, da Costa CE, Somda F, Aguilera D. Gastrointestinal Disorders in Peritoneal Dialysis Patients. Am J Nephrol. 2018;48(5):319–325. doi: 10.1159/000494145. - DOI - PubMed
    1. Strid H, Simren M, Johansson AC, Svedlund J, Samuelsson O, Bjornsson ES. The prevalence of gastrointestinal symptoms in patients with chronic renal failure is increased and associated with impaired psychological general well-being. Nephrology Dialysis Transpl. 2002;17(8):1434–1439. doi: 10.1093/ndt/17.8.1434. - DOI - PubMed
    1. Dong R, Guo ZY. Gastrointestinal symptoms in patients undergoing peritoneal dialysis: multivariate analysis of correlated factors. World J Gastroenterol. 2010;16(22):2812–2817. doi: 10.3748/wjg.v16.i22.2812. - DOI - PMC - PubMed

Publication types