Influence of Female Sex Hormones in Different Stages of Women on Periodontium
- PMID: 35264831
- PMCID: PMC8849144
- DOI: 10.4103/jmh.jmh_142_21
Influence of Female Sex Hormones in Different Stages of Women on Periodontium
Abstract
The primary etiologic factor for periodontal diseases is "Dental plaque." Although pathogenic bacteria in dental plaque are required for the incidence of periodontal disease, a susceptible host is also very important. The susceptibility of the host can be modified by many systemic factors with hormones level being one. The periodontium shows an exaggerated inflammatory response to plaque modified by female sex hormones during puberty, pregnancy, in women taking oral contraceptives, and at the postmenopausal stage. This review provides an in detail analysis of how periodontium is influenced by the fluctuation in sex steroid hormones of females during different phases of their lifetime and to discuss how much the same hormone at different ages and stages shows an exaggerated gingival response to plaque.
Keywords: Female sex hormones; menopause; periodontium; pregnancy; puberty.
Copyright: © 2022 Journal of Mid-life Health.
Conflict of interest statement
There are no conflicts of interest.
Similar articles
-
Influence of female sex hormones on periodontium: A case series.J Nat Sci Biol Med. 2015 Aug;6(Suppl 1):S146-9. doi: 10.4103/0976-9668.166124. J Nat Sci Biol Med. 2015. PMID: 26604605 Free PMC article.
-
Effects of endogenous sex hormones on the periodontium--review of literature.Aust Dent J. 2005 Sep;50(3):138-45. doi: 10.1111/j.1834-7819.2005.tb00352.x. Aust Dent J. 2005. PMID: 16238210 Review.
-
Female sex hormonal factors in periodontal disease.Ann Dent. 1976 Fall;35(3):42-6. Ann Dent. 1976. PMID: 788632 Review.
-
Targets for steroid hormone mediated actions of periodontal pathogens, cytokines and therapeutic agents: some implications on tissue turnover in the periodontium.Curr Drug Targets. 2000 Dec;1(4):309-25. doi: 10.2174/1389450003349119. Curr Drug Targets. 2000. PMID: 11467074 Review.
-
Sex steroid hormones and cell dynamics in the periodontium.Crit Rev Oral Biol Med. 1994;5(1):27-53. doi: 10.1177/10454411940050010201. Crit Rev Oral Biol Med. 1994. PMID: 7999949 Review.
Cited by
-
Oral Prevalence of Selenomonas noxia Differs among Orthodontic Patients Compared to Non-Orthodontic Controls: A Retrospective Biorepository Analysis.Pathogens. 2024 Aug 8;13(8):670. doi: 10.3390/pathogens13080670. Pathogens. 2024. PMID: 39204270 Free PMC article.
-
Understanding the Link Between Hormonal Changes and Gingival Health in Women: A Review.Cureus. 2025 Jun 3;17(6):e85270. doi: 10.7759/cureus.85270. eCollection 2025 Jun. Cureus. 2025. PMID: 40462880 Free PMC article. Review.
-
Oral manifestations in women using hormonal contraceptive methods: a systematic review.Clin Oral Investig. 2024 Mar 1;28(3):184. doi: 10.1007/s00784-024-05573-x. Clin Oral Investig. 2024. PMID: 38427087 Free PMC article.
-
Unusual localized gingival redness: a case report.Front Oral Health. 2023 Nov 28;4:1292332. doi: 10.3389/froh.2023.1292332. eCollection 2023. Front Oral Health. 2023. PMID: 38098979 Free PMC article.
-
Do more pregnancies increase the risk of periodontal disease?F1000Res. 2025 Feb 6;13:1238. doi: 10.12688/f1000research.155151.2. eCollection 2024. F1000Res. 2025. PMID: 40028450 Free PMC article.
References
-
- Socransky SS, Haffajee AD, Cugini MA, Smith C, Kent RL., Jr Microbial in complexes subgingival plaque. J Clinperiodontol. 1998;25:134–44. - PubMed
-
- Yucel Lindberg T, Båge T. Inflammatory mediators in the pathogenesis of periodontitis. Expert Rev Mol Med. 2013;15:e7. - PubMed
-
- Genco RJ, Borgnakke WS. Risk factors for periodontal disease. Periodontol 2000. 2013;62:59–94. - PubMed
-
- Loos BG, John RP, Laine ML. Identification of genetic risk factors for periodontitis and possible mechanisms of action. J Clin Periodontol. 2005;32(Suppl 6):159–79. - PubMed
-
- Nibali L, Donos N, Henderson B. Periodontal infectogenomics. J Med Microbiol. 2009;58:1269–74. - PubMed
Publication types
LinkOut - more resources
Full Text Sources