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Review
. 2022 Feb 24;11(5):1230.
doi: 10.3390/jcm11051230.

Arrhythmogenic Right Ventricular Cardiomyopathy and Differential Diagnosis with Diseases Mimicking Its Phenotypes

Nadine Molitor  1 , Firat Duru  1   2
Affiliations
Review

Arrhythmogenic Right Ventricular Cardiomyopathy and Differential Diagnosis with Diseases Mimicking Its Phenotypes

Nadine Molitor et al. J Clin Med. .

Abstract

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease, which is characterized by fibro-fatty replacement of predominantly the right ventricle (RV). The disease can result in ventricular tachyarrhythmias and sudden cardiac death. Our understanding of the pathophysiology and clinical expressivity of ARVC has been continuously evolving. The diagnosis can be challenging due to its variable expressivity, incomplete penetrance and the lack of specific diagnostic criteria. Idiopathic RV outflow tract tachycardia, Brugada Syndrome, athlete's heart, dilated cardiomyopathy, myocarditis, cardiac sarcoidosis, congenital aneurysms and diverticula may mimic clinical phenotypes of ARVC. This review aims to provide an update on the differential diagnosis of ARVC.

Keywords: Brugada syndrome; arrhythmogenic cardiomyopathy; athlete’s heart; dilated cardiomyopathy; myocarditis; outflow tract tachycardia; right ventricular.

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Conflict of interest statement

The authors declare no conflict of interest.

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