Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Feb 23;19(5):2563.
doi: 10.3390/ijerph19052563.

Sex, Gender and Health: Mapping the Landscape of Research and Policy

Affiliations

Sex, Gender and Health: Mapping the Landscape of Research and Policy

Lorraine Greaves et al. Int J Environ Res Public Health. .

Abstract

Including sex and gender considerations in health research is considered essential by many funders and is very useful for policy makers, program developers, clinicians, consumers and other end users. While longstanding confusions and conflations of terminology in the sex and gender field are well documented, newer conceptual confusions and conflations continue to emerge. Contemporary social demands for improved health and equity, as well as increased interest in precision healthcare and medicine, have made obvious the need for sex and gender science, sex and gender-based analyses (SGBA+), considerations of intersectionality, and equity, diversity and inclusion initiatives (EDI) to broaden representation among participants and diversify research agendas. But without a shared and precise understanding of these conceptual areas, fields of study, and approaches and their inter-relationships, more conflation and confusion can occur. This article sets out these areas and argues for more precise operationalization of sex- and gender-related factors in health research and policy initiatives in order to advance these varied agendas in mutually supportive ways.

Keywords: equity; equity, diversity & inclusion (EDI); gender; gender transformative; health; intersectionality; sex; sex and gender science; sex differences.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Canadian Organization for Sex and Gender (COGS) Research Sex & Gender Science (SGS) 2021. [(accessed on 24 December 2021)]. Available online: https://cogsresearch.ca/
    1. Schiebinger L., Klinge I., Paik H.Y., Sánchez de Madariaga I., Schraudner M., Stefanick M. Gendered Innovations in Science, Health & Medicine, Engineering, and Environment, 2011–2020. [(accessed on 24 December 2021)]. Available online: https://genderedinnovations.stanford.edu.
    1. Institute of Gender and Health Science Is Better with Sex and Gender: Strategic Plan 2018–2023. [(accessed on 24 December 2021)]. Available online: https://cihr-irsc.gc.ca/e/documents/igh_strategic_plan_2018-2023-e.pdf.
    1. Mastroianni A.C., Faden R., Federman D. Women and Health Research: Ethical and Legal Issues of Including Women in Clinical Studies. National Academies Press; Washington, DC, USA: 1994. - PubMed
    1. Ruiz-Cantero M.T., Pardo M.A. European Medicines Agency policies for clinical trials leave women unprotected. J. Epidemiol. Community Health. 2006;60:911–913. doi: 10.1136/jech.2006.048769. - DOI - PMC - PubMed

LinkOut - more resources