Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1986 Jul 31;138(2):611-7.
doi: 10.1016/s0006-291x(86)80540-x.

The complete amino acid sequence of human brain-derived acidic fibroblast growth factor

G Gimenez-Gallego, G Conn, V B Hatcher, K A Thomas
Comparative Study

The complete amino acid sequence of human brain-derived acidic fibroblast growth factor

G Gimenez-Gallego et al. Biochem Biophys Res Commun. .

Abstract

Acidic fibroblast growth factor is a potent mitogen for a variety of cells in culture, including vascular endothelial cells, and is angiogenic in vivo. The complete amino acid sequence of human brain-derived acidic fibroblast growth factor has been determined from amino terminal sequence analysis and carboxypeptidase A digestion of the whole protein and sequence analyses of peptides generated by tryptic, Staphylococcus aureus V8 protease and cyanogen bromide cleavages. A potential Asn-Gly-Ser glycosylation sequence is present in the human protein. The complete amino acid sequence is compared to that of the equivalent protein purified from bovine brain.

PubMed Disclaimer

Publication types

LinkOut - more resources