Overcoming drug resistance, the natural way
- PMID: 35271795
- DOI: 10.1016/j.chom.2022.02.008
Overcoming drug resistance, the natural way
Abstract
Colistin is an antibiotic of last resort for treating Gram-negative bacterial infections, but resistance is spreading rapidly. In a recent issue of Nature, Wang et al. use genome mining to identify and synthesize a natural variant that bypasses colistin resistance and offers new hope for tackling antimicrobial resistance.
Crown Copyright © 2022. Published by Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
-
A naturally inspired antibiotic to target multidrug-resistant pathogens.Nature. 2022 Jan;601(7894):606-611. doi: 10.1038/s41586-021-04264-x. Epub 2022 Jan 5. Nature. 2022. PMID: 34987225 Free PMC article.
