Hunger games in the host cell: Toxoplasma traps and skins host mitochondria
- PMID: 35271796
- DOI: 10.1016/j.chom.2022.02.010
Hunger games in the host cell: Toxoplasma traps and skins host mitochondria
Abstract
Toxoplasma gondii actively tethers host mitochondria to its vacuole, altering their function. In a recent issue of Science, Li et al. demonstrate that Toxoplasma disarms host metabolic defenses by inducing the organelle to shed atypical large structures from its outer membrane to trap mitochondrial proteins that restrict parasite growth.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
-
Mitochondria shed their outer membrane in response to infection-induced stress.Science. 2022 Jan 14;375(6577):eabi4343. doi: 10.1126/science.abi4343. Epub 2022 Jan 14. Science. 2022. PMID: 35025629
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources