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. 2022 Feb;16(1):95-101.
doi: 10.14444/8199. Epub 2022 Mar 10.

Impact of Cervical Disc Arthroplasty vs Anterior Cervical Discectomy and Fusion on Driving Disability: Post Hoc Analysis of a Randomized Controlled Trial With 10-Year Follow-Up

Deeptee Jain  1 , Michael P Kelly  2 , Matthew F Gornet  3 , J Kenneth Burkus  4 , Scott D Hodges  5 , Randall F Dryer  6 , Jeffrey R McConnell  7 , Todd H Lanman  8 , K Daniel Riew  9
Affiliations

Impact of Cervical Disc Arthroplasty vs Anterior Cervical Discectomy and Fusion on Driving Disability: Post Hoc Analysis of a Randomized Controlled Trial With 10-Year Follow-Up

Deeptee Jain et al. Int J Spine Surg. 2022 Feb.

Abstract

Background: Driving an automobile requires the ability to turn the neck laterally. Anecdotally, patients with multilevel fusions often complain about restricted turning motion. The purpose of this study was to compare the effectiveness of cervical disc arthroplasty (CDA) with anterior cervical discectomy and fusion (ACDF) on driving disability improvement at 10-year follow-up after a 2-level procedure.

Methods: In the original randomized controlled trial, patients with cervical radiculopathy or myelopathy at 2 levels underwent CDA or ACDF. The driving disability question from the Neck Disability Index was rated from 0 to 5 years preoperatively and up to 10 years postoperatively. Severity of driving disability was categorized into "none" (score 0), "mild" (1 or 2), and "severe" (3, 4, or 5). Score and severity were compared between groups.

Results: Out of 397 patients, 148 CDA and 118 ACDF patients had 10-year follow-up. Driving disability scores were not different between the groups preoperatively (CDA: 2.65; ACDF: 2.71, P = 0.699). Postoperatively, the scores in the CDA group were significantly lower than those in the ACDF group at 5 (0.60 vs 1.08, P ≤ 0.001) and 10 years (0.66 vs 1.07, P = 0.001). Mean score improvement in the CDA group was significantly greater than the ACDF group at 10-year follow-up (-1.94 vs -1.63, P = 0.003). The majority of patients reported severe driving disability (CDA: 56.9%, ACDF: 58.0%, P = 0.968) before surgery. After surgery, a greater proportion of patients in the CDA group had neck pain-free driving compared with the ACDF group at 5 (63.3% vs 41.8%, P < 0.001) and 10 years (61.8% vs 41.2%, P = 0.003).

Conclusion: In patients with cervical radiculopathy/myelopathy and 2-level disease, CDA provided greater improvements in driving disability as compared with ACDF at 10-year follow-up. This is the first report of its kind. This finding may be attributable to preservation of motion associated with CDA.

Clinical relevence: This study provides valuable information regarding the improvement of driving disability after both CDA and ACDF. It demonstrates that both procedures result in significant improvements, with CDA resulting in even better improvements than ACDF, up to 10 year follow-up.

Keywords: anterior cervical discectomy; cervical disc arthroplasty; driving disability; fusion.

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Conflict of interest statement

Disclosures: K. Daniel Riew reports royalties or licenses from Biomet; consulting fees from NuVasive and Happe Spine; a leadership role with NASS; and stock or stock options from Axiomed, Expanding Orthopedics, Spineology, Spinal Kinetics, Amedica, Vertiflex, Benvenue, and Paradigm Spine. Todd Lanman reports royalties from Stryker, NuVasive, and Choice Spine. Deeptee Jain reports consulting fees from Kaia Health and Medtronic. Matthew Gornet reports royalties or licenses from Medtronic, RTI, and Pioneer Surgical; consulting fees from Aesculap; and stock or stock options from Bonovo, International Spine & Orthopedic Institute, LLLC, Nocimed, OuroBoros, and RTI. Michael Kelly reports grants or contracts from OMeGA, the Setting Scoliosis Straight Foundation, the International Spine Study Group Foundation, and the Scoliosis Research Society; and a leadership role with the Scoliosis Research Society and Spine. The remaining authors have no disclosures.

Figures

Figure 1
Figure 1
Mean driving disability scores in cervical disc arthroplasty (CDA) vs anterior cervical discectomy (ACDF) and fusion patients over time. P values represent the results of Wilcoxon rank-sum test comparing treatment groups.
Figure 2
Figure 2
Summary and comparison of driving disability severity groups in cervical disc arthroplasty (CDA) vs anterior cervical discectomy and fusion (ACDF) patients over time. P values represent the results of the Fisher exact test.
See this image and copyright information in PMC

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