Discovering missing heritability in whole-genome sequencing data

Alexander I Young^{1

2}

Affiliations

¹ Human Genetics Department, UCLA David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. alextisyoung@gmail.com.
² UCLA Anderson School of Management, Los Angeles, CA, USA. alextisyoung@gmail.com.

Comment

Alexander I Young. Nat Genet. 2022 Mar.

. 2022 Mar;54(3):224-226.

doi: 10.1038/s41588-022-01012-3.

Alexander I Young^{1

2}

¹ Human Genetics Department, UCLA David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. alextisyoung@gmail.com.
² UCLA Anderson School of Management, Los Angeles, CA, USA. alextisyoung@gmail.com.

No abstract available

Comment on

Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data.
Wainschtein P, Jain D, Zheng Z; TOPMed Anthropometry Working Group; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Cupples LA, Shadyab AH, McKnight B, Shoemaker BM, Mitchell BD, Psaty BM, Kooperberg C, Liu CT, Albert CM, Roden D, Chasman DI, Darbar D, Lloyd-Jones DM, Arnett DK, Regan EA, Boerwinkle E, Rotter JI, O'Connell JR, Yanek LR, de Andrade M, Allison MA, McDonald MN, Chung MK, Fornage M, Chami N, Smith NL, Ellinor PT, Vasan RS, Mathias RA, Loos RJF, Rich SS, Lubitz SA, Heckbert SR, Redline S, Guo X, Chen Y-I, Laurie CA, Hernandez RD, McGarvey ST, Goddard ME, Laurie CC, North KE, Lange LA, Weir BS, Yengo L, Yang J, Visscher PM. Wainschtein P, et al. Nat Genet. 2022 Mar;54(3):263-273. doi: 10.1038/s41588-021-00997-7. Epub 2022 Mar 7. Nat Genet. 2022. PMID: 35256806 Free PMC article.

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