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. 2022 Jan-Mar;15(Spec 1):285-288.
doi: 10.5935/1984-0063.20220001.

Pitfalls of AHI system of severity grading in obstructive sleep apnoea

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Pitfalls of AHI system of severity grading in obstructive sleep apnoea

Rashmi Soori et al. Sleep Sci. 2022 Jan-Mar.

Abstract

Obstructive sleep apnoea (OSA) is the major underlying co-morbidity in many of the non-communicable diseases (NCD) due to obesity as a common risk factor. Incidence and prevalence of OSA is on the constant rise ever since this entity came to forefront three decades ago. Precise treatment of underlying OSA is extremely important in major NCDs like diabetes mellitus, hypertension, endocrine disorders and vascular diseases. OSA is subcategorized in to mild, moderate and severe based of apnoea-hypopnea index (AHI). Based on the severity grading, treatment of OSA ranges from life style modifications to oral appliances, continuous positive airway pressure (CPAP) and surgeries. AHI system of severity grading in OSA has several inherent shortcomings and using AHI system for severity grading as the holy grail is likely to be counter-productive. AHI system equates apnoea and hypopnea as equal events, whereas physiological effects vary significantly. AHI system does not account duration of apnoea or body position during apnoeic events. We discuss at length the pitfalls of AHI system of severity grading in OSA.

Keywords: Obstructive; Sleep Apnea; Sleep Apnea Syndromes; Sleep Stages.

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References

    1. Kapur VK, Auckley DH, Chowdhuri S, Kuhlmann DC, Mehra R, Ramar K, Harrod CG. Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American Academy of Sleep Medicine clinical practice guideline. Journal of Clinical Sleep Medicine. 2017 Mar 15;13(03):479–504. - PMC - PubMed
    1. Tsara V, Amfilochiou A, Papagrigorakis MJ, Georgopoulos D, Liolios E. Guidelines for diagnosis and treatment of sleep-related breathing disorders in adults and children. Definition and classification of sleep related breathing disorders in adults: different types and indications for sleep studies (Part 1) Hippokratia. 2009 Jul;13(3):187–191. - PMC - PubMed
    1. Rapoport DM. POINT: is the apnea-hypopnea index the best way to quantify the severity of sleep-disordered breathing? Yes. Chest. 2016 Jan 1;149(1):14–16. - PubMed
    1. Kendzerska T, Gershon AS, Hawker G, Leung RS, Tomlinson G. Obstructive sleep apnea and risk of cardiovascular events and all-cause mortality: a decade-long historical cohort study. PLoS medicine. 2014 Feb 4;11(2):e1001599. - PMC - PubMed
    1. Giridhar BH, Rajesh V, Soori Rashmi, Rao Anusha, Verma Sanjay. Is Severity of Obstructive Sleep Apnoea Is A Surrogate Marker Of Cpap Titration Pressure?

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