Old pathways - New crossroads: Class 3 PI3K acts on glucocorticoid signal transduction
- PMID: 35276033
- DOI: 10.1111/apha.13812
Old pathways - New crossroads: Class 3 PI3K acts on glucocorticoid signal transduction
Comment on
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Class 3 phosphoinositide 3-kinase promotes hepatic glucocorticoid receptor stability and transcriptional activity.Acta Physiol (Oxf). 2022 May;235(1):e13793. doi: 10.1111/apha.13793. Epub 2022 Feb 7. Acta Physiol (Oxf). 2022. PMID: 35094500 Free PMC article.
References
REFERENCES
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- Weikum ER, Knuesel MT, Ortlund EA, Yamamoto KR. Glucocorticoid receptor control of transcription: precision and plasticity via allostery. Nat Rev Mol Cell Biol. 2017;18(3):159-174.
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- Nemazanyy I, Montagnac G, Russell RC, et al. Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. Nat Commun. 2015;6:8283.
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