Pregnancy-Associated Liver Diseases

Abstract

The liver disorders unique to pregnancy include hyperemesis gravidarum, intrahepatic cholestasis of pregnancy, acute fatty liver of pregnancy, and preeclampsia-associated hepatic impairment, specifically hemolysis, elevated liver enzymes, and low platelet count syndrome (HELLP). Their importance lies in the significant maternal and fetal/neonatal morbidity and mortality. Expeditious diagnosis and clinical evaluation is critical to ensure timely, appropriate care and minimize risks to the pregnant woman and her fetus/baby. A multidisciplinary approach is essential, including midwives, maternal-fetal-medicine specialists, anesthetists, neonatologists, and hepatologists.

Keywords: Acute Fatty Liver of Pregnancy; Gestational Liver Disease; HELLP Syndrome; Hyperemesis Gravidarum; Intrahepatic Cholestasis of Pregnancy; Maternal Health; Preeclampsia.