Ambulatory Glucose Profile (AGP) Report in Daily Care of Patients with Diabetes: Practical Tips and Recommendations

Abstract

The ambulatory glucose profile (AGP) is now established as the standardised, practical one-page report for graphically presenting a summary of glycaemic control status in patients with diabetes who use continuous glucose monitoring (CGM) systems as part of their daily diabetes care. The AGP report provides both a visual and a statistical summary of the glucose metrics that, as agreed in the 2019 international consensus for assessing glycaemic control, should be analysed in all people with diabetes who are using CGM systems. The AGP report can be analysed in a systematic fashion to understand current glycaemic control and to monitor, in real time, the impact of adjustments to therapy in both type 1 diabetes and type 2 diabetes. Here we provide a practical guide to the glycaemic measures that are summarised in the AGP Report and illustrate the essential components of an AGP review in a series of hypothetical, real-world, patient-centred case studies (see Supplementary Materials).

Keywords: Ambulatory glucose profile (AGP); Continuous glucose monitoring (CGM); Type 1 diabetes; Type 2 diabetes.

Fig. 1

Ambulatory glucose profile (AGP) report

Fig. 2

Algorithm for the assessment and interpretation of an AGP report. This simple algorithm illustrates the flow of activities that should be followed when interpreting an AGP report, starting at the top with an assessment of the data quality. AGP ambulatory glucose profile, CGM continuous glucose monitoring