Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Published Erratum
. 2022 Mar 12;41(1):93.
doi: 10.1186/s13046-022-02292-7.

Correction to: Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8+ T cell exclusion

Wenli Fang  1 , Ting Zhou  1 , He Shi  1 , Mengli Yao  1 , Dian Zhang  1 , Husun Qian  1 , Qian Zeng  1 , Yange Wang  1 , Fangfang Jin  1 , Chengsen Chai  1 , Tingmei Chen  2
Affiliations
Published Erratum

Correction to: Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8+ T cell exclusion

Wenli Fang et al. J Exp Clin Cancer Res. .
No abstract available

PubMed Disclaimer

Figures

Fig. 3
Fig. 3
PGRN/STAT3 axis regulates TAMs polarization and up-regulates PD-L1 expression. a After being treated with PGRN, western blot was used to detect STAT3/pSTAT3, AKT/pAKT and ERK1/2/pERK1/2 expression in M2. b M2 was exposed to PGRN at a specified time point, and WB was used to detect the expression of downstream signaling proteins of PGRN. c-d M2 was pretreated with STAT3 inhibitor Stattic, and then PGRN was added. Expression of PD-L1, STAT3/pSTAT3 and Arg1 was examined by Western blotting. e-f M2 was pretreated with AKT inhibitor LY294002 and ERK1/2 inhibitor U0126 respectively, and the expression changes of PD-L1, STAT3/pSTAT3 and Arg1 before and after PGRN stimulation were analyzed by Western blot
See this image and copyright information in PMC

Erratum for

References

    1. Fang W, Zhou T, Shi H, et al. Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8+ T cell exclusion. J Exp Clin Cancer Res. 2021;40:4. doi: 10.1186/s13046-020-01786-6. - DOI - PMC - PubMed

Publication types