Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Feb 25:13:838027.
doi: 10.3389/fendo.2022.838027. eCollection 2022.

Prevalence, Deaths and Disability-Adjusted-Life-Years (DALYs) Due to Type 2 Diabetes and Its Attributable Risk Factors in 204 Countries and Territories, 1990-2019: Results From the Global Burden of Disease Study 2019

Saeid Safiri  1   2 , Nahid Karamzad  3 , Jay S Kaufman  4 , Arielle Wilder Bell  5   6 , Seyed Aria Nejadghaderi  2   7 , Mark J M Sullman  8   9 , Maziar Moradi-Lakeh  10 , Gary Collins  11   12 , Ali-Asghar Kolahi  13
Affiliations

Prevalence, Deaths and Disability-Adjusted-Life-Years (DALYs) Due to Type 2 Diabetes and Its Attributable Risk Factors in 204 Countries and Territories, 1990-2019: Results From the Global Burden of Disease Study 2019

Saeid Safiri et al. Front Endocrinol (Lausanne). .

Abstract

Aim: To report the point prevalence, deaths and disability-adjusted-life-years (DALYs) due to type 2 diabetes and its attributable risk factors in 204 countries and territories during the period 1990-2019.

Methods: We used the data of the Global Burden of Disease (GBD) Study 2019 to report number and age-standardised rates per 100 000 population of type 2 diabetes. Estimates were reported with 95% uncertainty intervals (UIs).

Results: In 2019, the global age-standardised point prevalence and death rates for type 2 diabetes were 5282.9 and 18.5 per 100 000, an increase of 49% and 10.8%, respectively, since 1990. Moreover, the global age-standardised DALY rate in 2019 was 801.5 per 100 000, an increase of 27.6% since 1990. In 2019, the global point prevalence of type 2 diabetes was slightly higher in males and increased with age up to the 75-79 age group, decreasing across the remaining age groups. American Samoa [19876.8] had the highest age-standardised point prevalence rates of type 2 diabetes in 2019. Generally, the burden of type 2 diabetes decreased with increasing SDI (Socio-demographic Index). Globally, high body mass index [51.9%], ambient particulate matter pollution [13.6%] and smoking [9.9%] had the three highest proportions of attributable DALYs.

Conclusion: Low and middle-income countries have the highest burden and greater investment in type 2 diabetes prevention is needed. In addition, accurate data on type 2 diabetes needs to be collected by the health systems of all countries to allow better monitoring and evaluation of population-level interventions.

Keywords: burden; global epidemiology; mortality; prevalence; type 2 diabetes mellitus; worldwide epidemiology.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Age-standardized point prevalence (A) and death (B) rate of type 2 diabetes per 100,000 population in 2019, by country. (Generated from data available from http://ghdx.healthdata.org/gbd-results-tool).
Figure 2
Figure 2
Percentage change in age-standardized point prevalence (A) and deaths (B) rate of type 2 diabetes per 100,000 population from 1990 to 2019, by country. (Generated from data available from http://ghdx.healthdata.org/gbd-results-tool).
Figure 3
Figure 3
Global number of prevalent cases and prevalence of type 2 diabetes per 100,000 population by age and sex in 2019; Dotted and dashed lines indicate 95% upper and lower uncertainty intervals, respectively. (Generated from data available from http://ghdx.healthdata.org/gbd-results-tool).
Figure 4
Figure 4
Age-standardized DALY rates of type 2 diabetes for 204 countries and territories by SDI, in 2019; Expected values based on the Socio-demographic Index and disease rates in all locations are shown as the black line. Each point shows the observed age-standardized DALY rate for each country in 2019. DALY=disability adjusted life years. SDI= Socio-demographic Index (Generated from data available from http://ghdx.healthdata.org/gbd-results-tool).
Figure 5
Figure 5
Percentage of DALYs due to type 2 diabetes attributable to risk factors for 21 GBD regions in 2019. DALY, disability adjusted life years (Generated from data available from http://ghdx.healthdata.org/gbd-results-tool).
See this image and copyright information in PMC

References

    1. Baena-Díez JM, Peñafiel J, Subirana I, Ramos R, Elosua R, Marín-Ibañez A, et al. . Risk of Cause-Specific Death in Individuals With Diabetes: A Competing Risks Analysis. Diabetes Care (2016) 39(11):1987–95. doi: 10.2337/dc16-0614 - DOI - PubMed
    1. Zhou B, Lu Y, Hajifathalian K, Bentham J, Di Cesare M, Danaei G, et al. . Worldwide Trends in Diabetes Since 1980: A Pooled Analysis of 751 Population-Based Studies With 4· 4 Million Participants. Lancet (2016) 387(10027):1513–30. doi: 10.1016/S0140-6736(16)00618-8 - DOI - PMC - PubMed
    1. Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, et al. . Global and Regional Diabetes Prevalence Estimates for 2019 and Projections for 2030 and 2045: Results From the International Diabetes Federation Diabetes Atlas. Diabetes Res Clin Pract (2019) 157:107843. doi: 10.1016/j.diabres.2019.107843 - DOI - PubMed
    1. Roth GA, Abate D, Abate KH, Abay SM, Abbafati C, Abbasi N, et al. . Global, Regional, and National Age-Sex-Specific Mortality for 282 Causes of Death in 195 Countries and Territories, 1980–2017: A Systematic Analysis for the Global Burden of Disease Study 2017. Lancet (2018) 392(10159):1736–88. doi: 10.1016/S0140-6736(18)32203-7 - DOI - PMC - PubMed
    1. Yu M, Zhan X, Yang Z, Huang Y. Measuring the Global, Regional, and National Burden of Type 2 Diabetes and the Attributable Risk Factors in All 194 Countries. J Diabetes (2021) 13:613–39. doi: 10.1111/1753-0407.13159 - DOI - PubMed

Publication types