Diagnostic-therapeutic algorithm for thrombotic microangiopathy. A report of two cases

Abstract

Thrombotic microangiopathies (TMA) are a group of clinical syndromes associated with haemolytic anaemia, thrombocytopenia and organ dysfunction, mainly renal or neurological. They are associated with significant morbidity and mortality, so early diagnosis and treatment are essential. In this article we report two cases of TMA; a patient with thrombotic thrombocytopenic purpura (TTP) and a patient with atypical haemolytic uraemic syndrome (aHUS).

Keywords: ADAMTS13; Eculizumab; Hemolytic uremic syndrome; Microangiopatía trombótica; Púrpura trombocitopénica trombótica; Síndrome hemolítico urémico; Thrombotic microangiopathy; Thrombotic thrombocytopenic purpura.