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. 2022 Apr:76:103462.
doi: 10.1016/j.amsu.2022.103462. Epub 2022 Mar 8.

National early warning score (NEWS) 2 predicts hospital mortality from COVID-19 patients

Eric Wibisono  1 , Usman Hadi  1 , Bramantono  1 , Muhammad Vitanata Arfijanto  1 , Musofa Rusli  1 , Brian Eka Rahman  1   2 , Tri Pudy Asmarawati  1   2 , Miftahani Leo Choirunnisa  1 , Dwi Retno Puji Rahayu  1
Affiliations

National early warning score (NEWS) 2 predicts hospital mortality from COVID-19 patients

Eric Wibisono et al. Ann Med Surg (Lond). 2022 Apr.

Abstract

Background: COVID-19 has a high risk of mortality, especially in patients with comorbid diseases such as cardiac disease, type 2 diabetes mellitus, chronic kidney disease, and hypertension. The National Early Warning Score (NEWS) is a tool that helps in identifying changes in patient conditions that require intensive treatment.

Objective: Analyzing NEWS-2 to identify the risk of death in COVID-19 patients.

Methods: This research was conducted from June to July 2020 by using quota sampling. The number of participants in this study was 112 participants (case group = 56 participants and control group = 56 participants). Participants were assessed for NEWS-2 and evaluated for their treatment outcomes. The analysis used in this study was the Chi-squared test and logistic regression with p < 0.05.

Results: 45 participants died of having NEWS-2 score >5, and as many as 50 participants showed an improvement in their condition by having NEWS-2 score 5 (OR = 34.091; p < 0.001). The accuracy of NEWS-2's assessment of mortality of COVID-19 patients had a sensitivity of 80.4% and a specificity of 89.3%. There were several comorbid diseases that had a significant relationship on mortality of COVID-19 patients such as cardiac disease (β = 5.907; 1.107-31.527 95% CI; p = 0.038), T2DM (β = 3.143; 1.269-7.783 95% CI; p = 0.013), CKD (β = 3.851; 1.195-12.416 95% CI; p = 0.024), and hypertension (β = 2.820; 1.075-7.399 95% CI; p = 0.035).

Conclusion: The NEWS-2 can be used to identify the risk of death of COVID-19 patients.

Keywords: COVID-19; Comorbid disease; Mortality; National early warning score.

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Conflict of interest statement

The authors have no conflict of interest.

Figures

Fig. 1
Fig. 1
Cut-off NEWS-2 based on case and control groups of COVID-19 patients.
See this image and copyright information in PMC

References

    1. Nugraha B., Wahyuni L.K., Laswati H., Kusumastuti P., Tulaar A.B., Gutenbrunner C. COVID-19 pandemic in Indonesia: situation and challenges of rehabilitation medicine in Indonesia. Acta Medica Indonesiana. 2020;52(3):299–305. - PubMed
    1. Mahendradhata Y., Andayani N., Hasri E.T., Arifi M.D., Siahaan R.G.M., Solikha D.A., et al. The capacity of the Indonesian Healthcare system to respond to COVID-19. Front. Public Health. 2021;9:649819. doi: 10.3389/fpubh.2021.649819. - DOI - PMC - PubMed
    1. Rozaliyani A., Savitri A.I., Setianingrum F., Shelly T.N., Ratnasari V., Kuswindarti R., et al. Factors associated with death in COVID-19 patients in Jakarta, Indonesia: an epidemiological study. Acta Medica Indonesiana. 2020;52(3):246–254. - PubMed
    1. de Roquetaillade C., Bredin S., Lascarrou J.B., Soumagne T., Cojocaru M., Chousterman B.G., et al. Timing and causes of death in severe COVID-19 patients. Crit. Care. 2021;25(1):224. doi: 10.1186/s13054-021-03639-w. - DOI - PMC - PubMed
    1. Covino M., Sandroni C., Santoro M., Sabia L., Simeoni B., Bocci M.G., et al. Predicting intensive care unit admission and death for COVID-19 patients in the emergency department using early warning scores. Resuscitation. 2020;156:84–91. doi: 10.1016/j.resuscitation.2020.08.124. - DOI - PMC - PubMed