Thermal paper as a potential source of bisphenol A for humans and the environment: migration and ecotoxicological impact

Abstract

The objective of this work was to evaluate thermal paper (TP) tickets used in Argentina as a potential source of bisphenol A (BPA) that could impact humans and the environment. BPA in TP was measured by HPLC ranging from 11.1 to 30.5 mg BPAg^-1. In order to estimate the impact on humans, dermal BPA estimated daily intake was calculated as being 79.3 ± 19.5 μgd^-1 for workers and 1.6 ± 0.4 μgd^-1 for the general population. To evaluate TP's impact on the environment, BPA migration from TP to water and soil was studied. In the case of water, 99.6% of the BPA tickets content migrated in 30 h, while 78.0% moved into the soil in 96 h. BPA degradation kinetics in soil and water were also carried out; while in soil 61.9% of BPA degraded in 120 h, no degradation was observed up to 120 h in tap or river water.Additionally, ecotoxicological effects of BPA on the earthworm Eisenia andrei, a representative terrestrial indicator, were studied performing bioassays on lethality, avoidance, and reproductive and enzymatic activity. BPA showed to be very toxic to E. andrei (LC₅₀ value in contact paper test of 17 μgcm^-2, 95% confidence interval 6-46 μgcm^-2, 24 h exposure) and also caused an increase of total cocoons for earthworms exposed to 10 and 50 mg BPA kg^-1 soil. Evasion response was observed at a concentration of 50 mg BPA kg^-1 soil, while no effect was observed on cholinesterases, carboxylesterases, and glutathione S-transferases activities (1, 10, and 50 mg BPA kg^-1 soil). Finally, a simple BPA degradation technology using water peroxide and radish (Raphanus sativus) tissue as catalyst was explored as a simple and domestic potential treatment to avoid BPA migration to the environment.

Keywords: Bisphenol A; Degradation; Eisenia andrei; Migration; Raphanus sativus; Thermal paper.