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. 2022 Mar 24;65(6):4496-4499.
doi: 10.1021/acs.jmedchem.2c00339. Epub 2022 Mar 14.

Antibody-Drug Conjugates for Immunology

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Antibody-Drug Conjugates for Immunology

Peter S Dragovich. J Med Chem. .

Abstract

The application of antibody-drug conjugates (ADCs) to fields outside of oncology is increasing but is still relatively uncommon. A recent publication describes the conjugation of glucocorticoid receptor modulators to antibodies as a means of improving the separation between desired anti-inflammatory activity and unwanted systemic side effects.

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