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Comment
. 2022 May;19(5):281-282.
doi: 10.1038/s41575-022-00600-2.

Location, location, location - spatial insight into hepatic macrophage populations

Affiliations
Comment

Location, location, location - spatial insight into hepatic macrophage populations

Adrien Guillot et al. Nat Rev Gastroenterol Hepatol. 2022 May.
No abstract available

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Comment on

  • Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches.
    Guilliams M, Bonnardel J, Haest B, Vanderborght B, Wagner C, Remmerie A, Bujko A, Martens L, Thoné T, Browaeys R, De Ponti FF, Vanneste B, Zwicker C, Svedberg FR, Vanhalewyn T, Gonçalves A, Lippens S, Devriendt B, Cox E, Ferrero G, Wittamer V, Willaert A, Kaptein SJF, Neyts J, Dallmeier K, Geldhof P, Casaert S, Deplancke B, Ten Dijke P, Hoorens A, Vanlander A, Berrevoet F, Van Nieuwenhove Y, Saeys Y, Saelens W, Van Vlierberghe H, Devisscher L, Scott CL. Guilliams M, et al. Cell. 2022 Jan 20;185(2):379-396.e38. doi: 10.1016/j.cell.2021.12.018. Epub 2022 Jan 11. Cell. 2022. PMID: 35021063 Free PMC article.

References

    1. Guilliams, M. et al. Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches. Cell 185, 379–396 (2022). - DOI
    1. Ramachandran, P., Matchett, K. P., Dobie, R., Wilson-Kanamori, J. R. & Henderson, N. C. Single-cell technologies in hepatology: new insights into liver biology and disease pathogenesis. Nat. Rev. Gastroenterol. Hepatol. 17, 457–472 (2020). - DOI
    1. Saviano, A., Henderson, N. C. & Baumert, T. F. Single-cell genomics and spatial transcriptomics: discovery of novel cell states and cellular interactions in liver physiology and disease biology. J. Hepatol. 73, 1219–1230 (2020). - DOI
    1. Sheng, J. et al. Topological analysis of hepatocellular carcinoma tumour microenvironment based on imaging mass cytometry reveals cellular neighbourhood regulated reversely by macrophages with different ontogeny. Gut https://doi.org/10.1136/gutjnl-2021-324339 (2021).
    1. Karlsen, T. H. et al. The EASL-Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality. Lancet 399, 61–116 (2022). - DOI

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