Comment on

• Advances in the Design and Development of PROTAC-mediated HDAC Degradation.

  Rodrigues DA, Roe A, Griffith D, Chonghaile TN. Rodrigues DA, et al. Curr Top Med Chem. 2022 Mar 4;22(5):408-424. doi: 10.2174/1568026621666211015092047. Curr Top Med Chem. 2022. PMID: 34649488
• The Hybrid Compounds as Multi-target Ligands for the Treatment of Alzheimer's Disease: Considerations on Donepezil.

  Gulcan HO, Kosar M. Gulcan HO, et al. Curr Top Med Chem. 2022 Mar 4;22(5):395-407. doi: 10.2174/1568026621666211111153626. Curr Top Med Chem. 2022. PMID: 34766890 Review.
• Molecular Modeling Techniques Applied to the Design of Multitarget Drugs: Methods and Applications.

  Castro LHE, Sant'Anna CMR. Castro LHE, et al. Curr Top Med Chem. 2022 Mar 4;22(5):333-346. doi: 10.2174/1568026621666211129140958. Curr Top Med Chem. 2022. PMID: 34844540 Review.
• Natural Products as Sources of Multitarget Compounds: Advances in the Development of Ferulic Acid as Multitarget Therapeutic.

  Kaur R, Sood A, Lang DK, Arora R, Kumar N, Diwan V, Saini B. Kaur R, et al. Curr Top Med Chem. 2022 Mar 4;22(5):347-365. doi: 10.2174/1568026622666220117105740. Curr Top Med Chem. 2022. PMID: 35040403 Review.
• The Design of Multi-target Drugs to Treat Cardiovascular Diseases: Two (or more) Birds on One Stone.

  Caruso L, Nadur NF, da Fonseca MB, Peixoto Ferreira LA, Lacerda RB, Graebin CS, Kümmerle AE. Caruso L, et al. Curr Top Med Chem. 2022 Mar 4;22(5):366-394. doi: 10.2174/1568026622666220201151248. Curr Top Med Chem. 2022. PMID: 35105288 Review.