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. 2022 Feb 28;10(1):e2100161.
doi: 10.9745/GHSP-D-21-00161. Print 2022 Feb 28.

Extending Delivery of Seasonal Malaria Chemoprevention to Children Aged 5-10 Years in Chad: A Mixed-Methods Study

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Extending Delivery of Seasonal Malaria Chemoprevention to Children Aged 5-10 Years in Chad: A Mixed-Methods Study

Azoukalné Moukénet et al. Glob Health Sci Pract. .

Abstract

Background: To prevent malaria among children aged 3-59 months in areas with high seasonal transmission, seasonal malaria chemoprevention (SMC) is recommended. In Chad, there is evidence of SMC administration to children aged older than 5 years (referred to as "leakage"). This study aimed to understand the reasons for leakage and explore the feasibility and acceptability of extending the delivery of SMC to children aged 5-10 years in Chad.

Methods: We conducted a mixed-methods study in Massaguet health district with a cross-sectional survey to determine SMC coverage for children aged up to 10 years after SMC cycles 1 and 3 (n=90 and n=100 caregivers surveyed, respectively) and at the end of cycle 4 (n=101 caregivers surveyed). We conducted 14 key informant interviews at the national and district level and 8 focus group discussions with community distributors and caregivers.

Results: In the compounds surveyed, there were no children aged 5-10 years in cycle 1. In cycles 3 (n=1 children) and 4 (n=16 children), there was 100% (95% confidence interval [CI]=2.5, 100.0) and 62.5% (95% CI=35.4, 84.8) coverage of SMC in children aged 5-10 years, respectively. Extension of SMC to older children was considered acceptable, but there were concerns about feasibility and ensuring the sustainability of the current program in children aged 3-59 months. Key informants acknowledged the need to secure additional funding to pilot SMC in older age groups and were uncertain about the impact of the current SMC program at scale.

Conclusion: Key informants considered extending SMC to children aged 5-10 years acceptable but did not deem it a current priority. They expressed an urgent need to address leakage and reinforce both the sustainability and quality of the current SMC program.

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References

    1. World Health Organization (WHO). World Malaria Report 2019. WHO; 2019. Accessed January 25, 2022. https://www.who.int/publications/i/item/9789241565721
    1. Onwujekwe O, Uguru N, Etiaba E, Chikezie I, Uzochukwu B, Adjagba A. The economic burden of malaria on households and the health system in Enugu State southeast Nigeria. PLoS One. 2013;8(11):e78362. 10.1371/journal.pone.0078362. - DOI - PMC - PubMed
    1. Rogerson SJ, Desai M, Mayor A, Sicuri E, Taylor SM, van Eijk AM. Burden, pathology, and costs of malaria in pregnancy: new developments for an old problem. Lancet Infect Dis. 2018;18(4):e107–e118. 10.1016/S1473-3099(18)30066-5. - DOI - PubMed
    1. WHO Global Malaria Programme (GMP). Technical Expert Group (TEG) on Preventive Chemotherapy. Report of the Technical Consultation on Seasonal Malaria Chemoprevention (SMC). WHO; 2011. Accessed January 25, 2022. https://www.who.int/malaria/publications/atoz/smc_report_teg_meetingmay2...
    1. Meremikwu MM, Donegan S, Sinclair D, Esu E, Oringanje C. Intermittent preventive treatment for malaria in children living in areas with seasonal transmission. Cochrane Database Syst Rev. 2012;2012(2):CD003756. 10.1002/14651858.CD003756.pub4. - DOI - PMC - PubMed

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