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. 1986;27(1):115-23.
doi: 10.1186/BF03548564.

Colicin resistance in relation to pathogenicity factors in strains of Escherichia coli isolated from the intestinal tract of piglets

B K Djønne

Colicin resistance in relation to pathogenicity factors in strains of Escherichia coli isolated from the intestinal tract of piglets

B K Djønne. Acta Vet Scand. 1986.

Abstract
in English, German

Three hundred and fifteen E. coli strains isolated from the intestine of piglets were examined for K-antigens 88 and 99, enterotoxin production and colicin resistance. Of these strains 308 belonged to one of 3 following different groups: Group 1: 0149, K88, producing heat-labile (LT) and heat-stable (ST) enterotoxins, group 2: 064, K99, producing ST, and group 3: variable O-antigens, no K-antigens or enterotoxin production.

Almost 100 % of the E. coli strains were found to be resistant to colicins E1, E3, Ia, H and D+X. Resistance to colicins E2, B+M, V and K+X were found in 91.7 %, 43.8 %, 49.8 % and 62.2 % respectively.

E. coli strains in group 1 were always (resistant to colicin E2, while about 87 % of the other strains were resistant to this colicin. E. coli strains in group 2 were more often resistant to colicin B+M, V and K+X (65 %, 94 %, 83 %) than strains in group 1 (37 %, 24 %, 64 %) and strains in group 3 (37 %, 52 %, 46 %).

E. coli strains in group 2 showed a high degree of multiresistance, 45.1 % of the strains being resistant to all of the 9 colicins. About 10 % of the other strains were resistant to all of the 9 colicins.

E. coli strains harbouring the enteropathogenicity factors K99 antigen and ST production, showed a higher degree of colicin resistance than both the E. coli strains with K88 antigen and ST and LT production, and the E. coli strains lacking enteropathogenicity factors.

Forekomst av K-antigen 88 og 99, enterotoxin produksjon og colicin resistens ble undersøkt hos 315 E. coli-stammer isolert fra tynntarmen hos spedgris. Av disse stammene tilhørte 308 stammer en av følgende tre grupper: Gruppe 1: O149, K88, produksjon av både varmelabilt (LT) og varmestabilt (ST) enterotoxin, gruppe 2: 064, K99, ST produksjon eller gruppe 3: varierende O antigen uten påvisbare K-antigen eller enterotoxin produksjon.

Tilnærmet 100 % av alle stammene var resistente mot colicinene E1, E3, Ia, H og D+X. Resistens mot colicinene E2, B+M, V og K+X ble påvist hos henholdsvis 91,7 %, 43,8 %, 49,8 % og 62,2 % av stammene.

Alle E. coli-stammer i gruppe 1 var resistente mot colicin E2, mens omtrent 87 % av de resterende stammer var resistente mot colicin E2. Stammer i gruppe 2 var oftere resistente mot colicin B + M, V og K + X (65 %, 94 %, 83 %) enn stammer i gruppe 1 (37 24 %, 64 %) og stammer i gruppe 3 (37 %, 52 %, 46 %).

E. coli-stammer i gruppe 2 var ofte resistente mot flere coliciner, 45,1 % av disse stammene var resistente mot alle de ni undersøkte colicinene. Tilnærmet 10 % av de resterende stammene var resistente mot alle ni coliciner.

E. coli-stammer med enteropatogenitets faktorene K99 antigen og ST produksjon var i større grad resistente mot coliciner enn stammer som hadde K88 antigen, ST og LT produksjon og stammer uten enteropatogenitets faktorer.

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