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. 2022 Jun;32(2):192-193.
doi: 10.1177/15269248221087430. Epub 2022 Mar 18.

The 6 C's of Normothermic Regional Perfusion

James A Richards  1   2   3 , Rohit Gaurav  1   2   3 , Andrew J Butler  1   2   3 , Christopher J E Watson  1   2   3
Affiliations

The 6 C's of Normothermic Regional Perfusion

James A Richards et al. Prog Transplant. 2022 Jun.
No abstract available

Keywords: Normothermic Regional Perfusion (NRP); deceased donation; donation after circulatory death (DCD); liver transplantation; medical devices; normothermic machine perfusion (NMP); organ procurement.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Andrew Butler is part owner of a patent on the circuit used by the OrganOx metra device; he does not feel this has any relevance to this article. The remaining authors declare no conflicts of interest.

Figures

Figure 1.
Figure 1.
The 6Cs troubleshooting algorithm for Normothermic regional reperfusion.
See this image and copyright information in PMC

References

    1. Taylor R, Allen E, Richards JA, et al. Survival advantage for patients accepting the offer of a circulatory death liver transplant. J Hepatol. 2019;70(5):855‐865. doi:10.1016/j.jhep.2018.12.033 - DOI - PubMed
    1. Hessheimer AJ, Coll E, Torres F, et al. Normothermic regional perfusion vs. super-rapid recovery in controlled donation after circulatory death liver transplantation. J Hepatol. 2019;70(4):658‐665. doi:10.1016/j.jhep.2018.12.013 - DOI - PubMed
    1. Watson CJE, Hunt F, Messer S, et al. In situ normothermic perfusion of livers in controlled circulatory death donation may prevent ischemic cholangiopathy and improve graft survival. Am J Transplantn. 2019;19(6):1475‐1758. doi:10.1111/ajt.15241 - DOI - PubMed

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