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Comment
. 2022 May;19(5):284-285.
doi: 10.1038/s41569-022-00691-z.

An all-virtual clinical trial to assess a heart failure drug

Karina Huynh  1
Affiliations
Comment

An all-virtual clinical trial to assess a heart failure drug

Karina Huynh. Nat Rev Cardiol. 2022 May.

Abstract

The CHIEF-HF trial investigators employed a novel all-virtual study design to show that canagliflozin significantly reduces symptom burden in patients with heart failure.

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References

Original article

    1. Spertus JA, et al. The SGLT2 inhibitor canagliflozin in heart failure: the CHIEF-HF remote, patient-centered randomized trial. Nat. Med. 2022 doi: 10.1038/s41591-022-01703-8. - DOI - PMC - PubMed

Related article

    1. Cowie MR, et al. SGLT2 inhibitors: mechanisms of cardiovascular benefit beyond glycaemic control. Nat. Rev. Cardiol. 2020;17:761–772. doi: 10.1038/s41569-020-0406-8. - DOI - PubMed