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. 2022 Mar 1;5(3):e223073.
doi: 10.1001/jamanetworkopen.2022.3073.

Comparative Effectiveness of Single vs Repeated Rapid SARS-CoV-2 Antigen Testing Among Asymptomatic Individuals in a Workplace Setting

Bradley A Connor  1   2 , Marina Rogova  2 , Jefferson Garcia  2 , Darshan Patel  3 , Mara Couto-Rodriguez  4 , Dorottya Nagy-Szakal  4   5 , Michael Rendel  6   7
Affiliations

Comparative Effectiveness of Single vs Repeated Rapid SARS-CoV-2 Antigen Testing Among Asymptomatic Individuals in a Workplace Setting

Bradley A Connor et al. JAMA Netw Open. .

Abstract

This comparative effectiveness research study assesses the accuracy of single vs repeated antigen testing for diagnosis of COVID-19 among asymptomatic individuals in a workplace setting.

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Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Figures

Figure.
Figure.. Estimated Accuracy of SARS-CoV-2 Antigen Tests by Month and Comparison of Test Positivity Rates and Monthly Trends in Rates With New York City (NYC) Community Infection Rates
A, Estimated accuracy was calculated as the percentage of second antigen tests with a positive result for which the real-time reverse transcriptase–polymerase chain reaction (RT-qPCR) test result was also positive. B and C, The NYC infection rates are based on the percentage of people who tested positive through molecular (RT-qPCR) testing in NYC. The antigen-positive rates represent the percentage of people who tested positive by antigen testing among the total number of people tested. The true-positive rates represent the percentage of people who had positive RT-qPCR results among the total number of people tested. The false-positive rates represent the percentage of people who had positive antigen test results and negative RT-qPCR test results among the total number of people tested. Additional NYC data were obtained from NYC.gov. The company mandated vaccination for workers onsite in November 2021.
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References

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