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Comment
. 2022 Mar 17;29(3):353-355.
doi: 10.1016/j.chembiol.2022.03.004.

Inhibiting GLUTtony in cancer

Sarah M Chang  1 , Matthew G Vander Heiden  2
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Inhibiting GLUTtony in cancer

Sarah M Chang et al. Cell Chem Biol. .
Free article

Abstract

In this issue of Cell Chemical Biology, Olszewski et al. (2022) address the challenge of developing small molecules to inhibit glucose uptake in cancer. They characterize a novel pan-GLUT inhibitor that suppresses tumor growth and uncover how cancer cells can adapt to glucose restriction.

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Conflict of interest statement

Declaration of interests M.G.V.H. is a scientific advisor for Agios Pharmaceuticals, iTeos Therapeutics, Faeth Therapeutics, Sage Therapeutics, and Auron Therapeutics.

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