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Comment
. 2022 May:145:78-79.
doi: 10.1016/j.molimm.2022.03.001. Epub 2022 Mar 7.

Use of sulforaphane in COVID-19: Clinical trials are needed

Chia Siang Kow  1 , Dinesh Sangarran Ramachandram  2 , Syed Shahzad Hasan  3
Affiliations
Comment

Use of sulforaphane in COVID-19: Clinical trials are needed

Chia Siang Kow et al. Mol Immunol. 2022 May.

Abstract

We read with interest the narrative review authored by Kiser et al. (2021), which discussed extensively the antioxidant effect and anti-inflammatory effect of sulforaphane, a dietary supplement found in high amounts in cruciferous vegetables that ais orally accessible and well-tolerated. Notably, in their review, the authors also discussed the potential use of sulforaphane in patients with coronavirus disease 2019 (COVID-19). Sulforaphane mediates the inhibitory effect on NLRP3 inflammasome activation and we believe that this could be the main mechanism where sulforaphane is useful for patients with COVID-19.

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Conflict of interest statement

All authors declare no conflicts of interest.

Comment on

References

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