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. 2023 Apr;22(2):282-294.
doi: 10.1007/s12311-022-01391-7. Epub 2022 Mar 19.

Translation, Cross-Cultural Adaptation, and Validation to Brazilian Portuguese of the Cerebellar Cognitive Affective/Schmahmann Syndrome Scale

Stephanie Suzanne de Oliveira Scott  1 , José Luiz Pedroso  2 , Victor Vitalino Elias  3 , Paulo Ribeiro Nóbrega  1 , Emmanuelle Silva Tavares Sobreira  1   3 , Marcela Patrícia de Almeida  2 , Maria Thereza Drumond Gama  2 , Breno Kazuo Massuyama  2 , Orlando Graziani Povoas Barsottini  2 , Norberto Anizio Ferreira Frota  3   4 , Pedro Braga-Neto  5   6
Affiliations

Translation, Cross-Cultural Adaptation, and Validation to Brazilian Portuguese of the Cerebellar Cognitive Affective/Schmahmann Syndrome Scale

Stephanie Suzanne de Oliveira Scott et al. Cerebellum. 2023 Apr.

Erratum in

Abstract

Cerebellar cognitive affective syndrome (CCAS) is characterized by deficits in executive functions, language processing, spatial orientation, and affect regulation in patients with cerebellar disease. The symptoms can occur isolated or along with motor and coordination symptoms. The aim of our study was to translate and culturally adapt the CCAS scale to Brazilian Portuguese and validate the scale in our population. We performed a cross-sectional study with patients with primary and secondary ataxia. The study included 111 individuals, aged between 20 and 80 years, of both genders, 20 without cognitive and/or affective complaints who participated in the pre-test phase, 40 with cerebellar disease (hereditary/neurodegenerative ataxia or acquired/secondary cerebellar ataxia), and 51 healthy controls with no evidence of cognitive impairment and no affective symptoms matched for sex, age, and educational level. The scale was translated, culturally adapted, and validated. Statistical analysis of the data was performed, with association tests, mean comparison, and ROC curve analysis. Based on the analysis of the ROC curve, optimal cutoff values ​were found for each subitem of the scale. The translated and adapted scale has good internal consistency, is reproducible, has good reliability, and has the potential to be a reliable tool for screening cognitive symptoms in patients with cerebellar disease.

Keywords: Affect; Ataxia; Cerebellum; Cognition.

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References

    1. Schmahmann JD, Sherman JC. The cerebellar cognitive affective syndrome. Brain [Internet]. 1998;121:561–79. Available from: https://doi.org/10.1016/j.bandl.2009.07.006
    1. Hoche F, Guell X, Vangel MG, Sherman JC, Schmahmann JD. The cerebellar cognitive affective/Schmahmann syndrome scale. Brain. 2018;141(1):248–70. - DOI - PubMed
    1. Ziad S. Nasreddine, Phillips NA, Valerie Bédirian, Charbonneau S, Whitehead V, Collin I, et al. The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment. J Am Geriatr Soc. 2005;(53):695–9.
    1. Folstein MF, Folstein SE, McHugh PR. “Mini-mental state” a practical method for grading the cognitive state of patients for the clinician. J Psychiatry. 1975;12:189–98.
    1. Schmahmann JD. The cerebellum and cognition. Neurosci Lett [Internet]. 2019;688(April):62–75. Available from: https://doi.org/10.1016/j.neulet.2018.07.005

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