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Review
. 2022 May-Jun;97(3):362-365.
doi: 10.1016/j.abd.2021.03.014. Epub 2022 Mar 16.

Chronic mucocutaneous anogenital herpes: series of ten cases and literature review

Karina Baruel de Camargo Votto Calbucci  1 , John Verrinder Veasey  2
Affiliations
Review

Chronic mucocutaneous anogenital herpes: series of ten cases and literature review

Karina Baruel de Camargo Votto Calbucci et al. An Bras Dermatol. 2022 May-Jun.

Abstract

Anogenital herpes is one of the most prevalent sexually transmitted infections worldwide. It has several clinical manifestations, from cases of primary herpes infection to recurrent forms, among them chronic mucocutaneous herpes. This presentation is rare, characterized by a duration of more than four weeks, usually associated with immunosuppression and resistance to classic anti-herpetic treatment. The present study presents a series of ten cases of chronic mucocutaneous herpes with a discussion about its clinical, laboratory, and therapeutic aspects.

Keywords: Antiviral agents; Genital diseases, female; Genital diseases, male; Herpes genitalis; Herpes simplex.

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Figures

Figure 1
Figure 1
Chronic mucocutaneous herpes: clinical images of three male patients included in the study (A, Case 7; B, Case 6; C, Case 9).
Figure 2
Figure 2
Chronic mucocutaneous herpes: clinical images of three female patients with genital and gluteal lesions (A, Case 3; B, Case 2; C, Case 4).
Figure 3
Figure 3
: Smear of lesions submitted to rapid panoptic staining, showing multinucleated epithelial cells, called Tzanck cells, suggesting viral inclusion by herpes virus (×400).
Figure 4
Figure 4
Patient with hypertrophic chronic mucocutaneous herpes tumor. A, Pre-treatment. B, In the immediate postoperative period after surgical removal of the tumor lesion. C, After 4 weeks of surgical excision, with the surgical wound undergoing healing. D, After 10 weeks of the procedure, with the healed lesion.
See this image and copyright information in PMC

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