Epidemiology, reperfusion management, and outcomes of patients with myocardial infarction in Greece: The ILIAKTIS study

Ioannis Kanakakis¹, Panagiotis Stafylas², Grigorios Tsigkas³, Dimitris Nikas⁴, Andreas Synetos⁵, Dimitrios Avramidis⁶, Ioannis Tsiafoutis⁷, Anna Dagre⁸, Stergios Tzikas⁹, Giorgos Latsios⁵, Nikos Patsourakos¹⁰, Ilias Sanidas¹¹, Emmanouil Skalidis¹², Athanasios Pipilis¹³, Panagiotis Bamidis¹⁴, Periklis Davlouros³; for ILIAKTIS Investigators

Collaborators, Affiliations

Collaborators

for ILIAKTIS Investigators:
I Kanakakis, M E Tselegkidi, E Sertedaki, I Mamarelis, E Fraggos, E Mantzouranis, C Karvounis, A J Manolis, G Chatzilymperis, I Chiotelis, D Gryllis, L E Poulimenos, A Triantafyllis, D Alexopoulos, C Varlamos, G Almpanis, A Aggeli, A Sakkas, A Trikas, S Tsiamis, K Triantafylloy, D Mpenia, D Oikonomou, E Papadopoulou, D Avramidis, M Kousta, E Moulianitaki, G Poulianitis, G Mavrou, G Latsios, A Synetos, D Tousoulis, N Kafkas, S Godwin, G Mertzanos, M Koytouzis, I Tsiafoutis, A Papadopoulos, A Tsoumeleas, I Barbetseas, I Sanidas, A Athanasiou, I Paizis, A Kakkavas, T Papafanis, I Mantas, G Neroutsos, A Gkoliopoulou, V Tafrali, G Diakakis, K Grammatikopoulos, T Sinanis, A Kartalis, D Afendoulis, P Voutas, C Kardamis, A Doulis, N Kalantzis, K Vergis, C Chasikidis, G Armatas, A Damelou, M Ntogka, I Serafetinidis, K Zagkas, T Tselempis, P Makridis, I Karantoumanis, E Karapatsoudi, K Oikonomou, E Foukarakis, P Kafarakis, M Pitarokoilis, E Rogdakis, S Stavrakis, G Koudounis, V Karampetsos, N Lionakis, C Panotopoulos, D Svoronos, I Tsorlalis, K Tsatiris, E Beneki, N Papadopoulos, A Sawafta, D Kozatsani, G Spyromitros, I Bostanitis, G Dimitriadis, N Nikoloulis, N Kampouridis, V Giampatzis, S Patsilinakos, E Andrikou, N Katsiadas, G Papanagnou, A Kotsakis, E Ioannidis, N Platogiannis, S Psychari, E Pissimissis, G Gavrielatos, D Maritsa, N Papakonstantinou, N Patsourakos, G Oikonomou, K Katsanou, E Lazaris, N Moschos, T Giakoumakis, N Papagiannis, C Goudis, S Daios, K Devliotis, F Dimitriadis, M Giannadaki, M Savvidis, G Tsinopoulos, I Zarifis, T Askalidou, I Vasileiadis, P Kleitsiotou, S Sidiropoulos, A Tsaousidis, S Tzikas, V Vassilikos, C Papadopoulos, Ε Zarvalis, C Gogos, V Moschovidis, I Styliadis, V Laschos, K Spathoulas, I Vogiatzis, C Kasmeridis, A Papadopoulos, S Pittas, E Sdogkos, A Dagre, P Mpounas, I Rodis, A Pipilis, S Konstantinidis, S Makrygiannis, A Masdrakis, A Magginas, G Sevastos, G Katsimagklis, E Skalidis, S Petousis, P Davlouros, G Tsigkas, G Hahalis, E Koufou, D Tziakas, G Chalikias, A Thomaidi, D Stakos, A Chotidis, D Nikas, X Sakellariou, I Skoularigkis, A Dimos, N Iakovis, A Mpourazana, A Zagouras, G Lygkouri, P Bamidis, P Lagakis, D Spachos, P Stafylas, C V Chalitsios, M Karaiskou, C Tychala

Affiliations

¹ Catheterization Laboratory, Alexandra General Hospital, Athens, Greece. Electronic address: jkanakakis@yahoo.gr.
² HealThink (Medical Research & Innovation PC), Thessaloniki, Greece.
³ Medical School, University of Patras, Patra, Greece.
⁴ First Cardiology Clinic, Ioannina University Hospital, Ioannina, Greece.
⁵ First Department of Cardiology, Hippocratio Hospital, Athens Medical School, Athens, Greece.
⁶ General Hospital of Athens "G.Gennimatas" Hospital, Athens, Greece.
⁷ First Cardiology Department, Athens Red Cross Hospital, Athens, Greece.
⁸ General Hospital of Elefsina "Thriasio", Elefsina, Greece.
⁹ Third Department of Cardiology, Hippocratio Hospital, Aristotle University of Thessaloniki.
¹⁰ Cardiology Department, "Tzaneio" General Hospital of Piraeus, Greece.
¹¹ Department of Cardiology, LAIKO General Hospital, Athens, Greece.
¹² Department of Cardiology, Heraklion University Hospital, University of Crete Medical School, Heraklion, Greece.
¹³ Cardiology Department, Hygeia Hospital, Athens, Greece.
¹⁴ Medical School, Aristotle University of Thessaloniki, Greece.

PMID: 35307346
DOI: 10.1016/j.hjc.2022.03.003

Free article

Multicenter Study

Epidemiology, reperfusion management, and outcomes of patients with myocardial infarction in Greece: The ILIAKTIS study

Ioannis Kanakakis et al. Hellenic J Cardiol. 2022 Sep-Oct.

Free article

. 2022 Sep-Oct:67:1-8.

doi: 10.1016/j.hjc.2022.03.003. Epub 2022 Mar 17.

Authors

Collaborators

for ILIAKTIS Investigators:
I Kanakakis, M E Tselegkidi, E Sertedaki, I Mamarelis, E Fraggos, E Mantzouranis, C Karvounis, A J Manolis, G Chatzilymperis, I Chiotelis, D Gryllis, L E Poulimenos, A Triantafyllis, D Alexopoulos, C Varlamos, G Almpanis, A Aggeli, A Sakkas, A Trikas, S Tsiamis, K Triantafylloy, D Mpenia, D Oikonomou, E Papadopoulou, D Avramidis, M Kousta, E Moulianitaki, G Poulianitis, G Mavrou, G Latsios, A Synetos, D Tousoulis, N Kafkas, S Godwin, G Mertzanos, M Koytouzis, I Tsiafoutis, A Papadopoulos, A Tsoumeleas, I Barbetseas, I Sanidas, A Athanasiou, I Paizis, A Kakkavas, T Papafanis, I Mantas, G Neroutsos, A Gkoliopoulou, V Tafrali, G Diakakis, K Grammatikopoulos, T Sinanis, A Kartalis, D Afendoulis, P Voutas, C Kardamis, A Doulis, N Kalantzis, K Vergis, C Chasikidis, G Armatas, A Damelou, M Ntogka, I Serafetinidis, K Zagkas, T Tselempis, P Makridis, I Karantoumanis, E Karapatsoudi, K Oikonomou, E Foukarakis, P Kafarakis, M Pitarokoilis, E Rogdakis, S Stavrakis, G Koudounis, V Karampetsos, N Lionakis, C Panotopoulos, D Svoronos, I Tsorlalis, K Tsatiris, E Beneki, N Papadopoulos, A Sawafta, D Kozatsani, G Spyromitros, I Bostanitis, G Dimitriadis, N Nikoloulis, N Kampouridis, V Giampatzis, S Patsilinakos, E Andrikou, N Katsiadas, G Papanagnou, A Kotsakis, E Ioannidis, N Platogiannis, S Psychari, E Pissimissis, G Gavrielatos, D Maritsa, N Papakonstantinou, N Patsourakos, G Oikonomou, K Katsanou, E Lazaris, N Moschos, T Giakoumakis, N Papagiannis, C Goudis, S Daios, K Devliotis, F Dimitriadis, M Giannadaki, M Savvidis, G Tsinopoulos, I Zarifis, T Askalidou, I Vasileiadis, P Kleitsiotou, S Sidiropoulos, A Tsaousidis, S Tzikas, V Vassilikos, C Papadopoulos, Ε Zarvalis, C Gogos, V Moschovidis, I Styliadis, V Laschos, K Spathoulas, I Vogiatzis, C Kasmeridis, A Papadopoulos, S Pittas, E Sdogkos, A Dagre, P Mpounas, I Rodis, A Pipilis, S Konstantinidis, S Makrygiannis, A Masdrakis, A Magginas, G Sevastos, G Katsimagklis, E Skalidis, S Petousis, P Davlouros, G Tsigkas, G Hahalis, E Koufou, D Tziakas, G Chalikias, A Thomaidi, D Stakos, A Chotidis, D Nikas, X Sakellariou, I Skoularigkis, A Dimos, N Iakovis, A Mpourazana, A Zagouras, G Lygkouri, P Bamidis, P Lagakis, D Spachos, P Stafylas, C V Chalitsios, M Karaiskou, C Tychala

Affiliations

¹ Catheterization Laboratory, Alexandra General Hospital, Athens, Greece. Electronic address: jkanakakis@yahoo.gr.
² HealThink (Medical Research & Innovation PC), Thessaloniki, Greece.
³ Medical School, University of Patras, Patra, Greece.
⁴ First Cardiology Clinic, Ioannina University Hospital, Ioannina, Greece.
⁵ First Department of Cardiology, Hippocratio Hospital, Athens Medical School, Athens, Greece.
⁶ General Hospital of Athens "G.Gennimatas" Hospital, Athens, Greece.
⁷ First Cardiology Department, Athens Red Cross Hospital, Athens, Greece.
⁸ General Hospital of Elefsina "Thriasio", Elefsina, Greece.
⁹ Third Department of Cardiology, Hippocratio Hospital, Aristotle University of Thessaloniki.
¹⁰ Cardiology Department, "Tzaneio" General Hospital of Piraeus, Greece.
¹¹ Department of Cardiology, LAIKO General Hospital, Athens, Greece.
¹² Department of Cardiology, Heraklion University Hospital, University of Crete Medical School, Heraklion, Greece.
¹³ Cardiology Department, Hygeia Hospital, Athens, Greece.
¹⁴ Medical School, Aristotle University of Thessaloniki, Greece.

PMID: 35307346
DOI: 10.1016/j.hjc.2022.03.003

Abstract

Objective: Acute myocardial infarction (AMI) is one of the leading causes of death; however, updated data regarding clinical presentation and current management are missing in Greece. This study aimed to prospectively record the demographic and clinical characteristics of a representative sample of patients suffering from AMI, their management, and short-term outcomes.

Methods: ILIAKTIS is a national, prospective, multicenter, noninterventional study conducted under the auspices of Hellenic Society of Cardiology (HCS) and the European Initiative Stent - Save a Life. From 1^st April 2020 to 30^th June 2020, consecutive adult patients with STEMI or NSTEMI were enrolled in the 50 participating hospitals, appropriately selected to match the geographical and population distribution in the Greek territory.

Results: In total, 1862 patients (mean age: 64.2 ± 13.2 yrs.; 77.2% males) with AMI were enrolled. More patients presented with NSTEMI (56.8%) than with STEMI (43.2%). Primary PCI (pPCI) was the preferable treatment option for STEMI patients in PCI-hospitals (76.9% vs. 39.9% for non-PCI, p < .001) and thrombolysis in non-PCI-hospitals (47.3% vs. 17.9% for PCI-hospitals, p < .001). The mean length of hospital stay was 5.6 days. In-hospital mortality was less likely in NSTEMI compared to that in STEMI patients (aOR = 0.30; 95% CI 0.18 to 0.49). Patients initially admitted in non-PCI-hospitals showed increased risk for in-hospital (aOR = 2.29; 95% CI 1.20 to 4.42) and 30-day mortality (aOR = 1.88; 95% CI 1.20 to 2.96).

Conclusion: This study shows that the proportion of STEMI and NSTEMI patients managed interventionally has significantly increased, resulting in better clinical outcomes compared to previous Greek surveys.

Keywords: NSTEMI; STEMI; myocardial infarction; percutaneous coronary intervention; revascularization.

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Epidemiology, reperfusion management, and outcomes of patients with myocardial infarction in Greece: The ILIAKTIS study

Collaborators

Affiliations

Epidemiology, reperfusion management, and outcomes of patients with myocardial infarction in Greece: The ILIAKTIS study

Authors

Collaborators

Affiliations

Abstract

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Medical

Miscellaneous